CLCN6

Chloride channel 6, also known as CLCN6, is a human gene.

PBB_Summary
section_title =
summary_text = The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 6 and 7 belong to a subbranch of this family. Chloride channel 6 has four different alternatively spliced transcript variants. This gene is in close vicinity to two other kidney-specific chloride channel genes, CLCNKA and CLCNKB.cite web | title = Entrez Gene: CLCN6 chloride channel 6| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1185| accessdate = ]

ee also

* Chloride channel

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Nakajima D, Okazaki N, Yamakawa H, "et al." |title=Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. |journal=DNA Res. |volume=9 |issue= 3 |pages= 99–106 |year= 2003 |pmid= 12168954 |doi=10.1093/dnares/9.3.99
*cite journal | author=Nomura N, Nagase T, Miyajima N, "et al." |title=Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1. |journal=DNA Res. |volume=1 |issue= 5 |pages= 223–9 |year= 1995 |pmid= 7584044 |doi=10.1093/dnares/1.5.223
*cite journal | author=Brandt S, Jentsch TJ |title=ClC-6 and ClC-7 are two novel broadly expressed members of the CLC chloride channel family. |journal=FEBS Lett. |volume=377 |issue= 1 |pages= 15–20 |year= 1996 |pmid= 8543009 |doi=10.1016/0014-5793(95)01298-2
*cite journal | author=Eggermont J, Buyse G, Voets T, "et al." |title=Alternative splicing of ClC-6 (a member of the CIC chloride-channel family) transcripts generates three truncated isoforms one of which, ClC-6c, is kidney-specific. |journal=Biochem. J. |volume=325 ( Pt 1) |issue= |pages= 269–76 |year= 1997 |pmid= 9224655 |doi=
*cite journal | author=Eggermont J |title=The exon-intron architecture of human chloride channel genes is not conserved. |journal=Biochim. Biophys. Acta |volume=1397 |issue= 2 |pages= 156–60 |year= 1998 |pmid= 9565675 |doi=
*cite journal | author=Lamb FS, Clayton GH, Liu BX, "et al." |title=Expression of CLCN voltage-gated chloride channel genes in human blood vessels. |journal=J. Mol. Cell. Cardiol. |volume=31 |issue= 3 |pages= 657–66 |year= 1999 |pmid= 10198195 |doi= 10.1006/jmcc.1998.0901
*cite journal | author=Kornak U, Bösl MR, Kubisch C |title=Complete genomic structure of the CLCN6 and CLCN7 putative chloride channel genes(1). |journal=Biochim. Biophys. Acta |volume=1447 |issue= 1 |pages= 100–6 |year= 1999 |pmid= 10500249 |doi=
*cite journal | author=Lamb FS, Graeff RW, Clayton GH, "et al." |title=Ontogeny of CLCN3 chloride channel gene expression in human pulmonary epithelium. |journal=Am. J. Respir. Cell Mol. Biol. |volume=24 |issue= 4 |pages= 376–81 |year= 2001 |pmid= 11306429 |doi=
*cite journal | author=Tran P, Leclerc D, Chan M, "et al." |title=Multiple transcription start sites and alternative splicing in the methylenetetrahydrofolate reductase gene result in two enzyme isoforms. |journal=Mamm. Genome |volume=13 |issue= 9 |pages= 483–92 |year= 2003 |pmid= 12370778 |doi= 10.1007/s00335-002-2167-6
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, "et al." |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406
*cite journal | author=Gregory SG, Barlow KF, McLay KE, "et al." |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315–21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727

External links

*

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