OR3A3

OR3A3
Olfactory receptor, family 3, subfamily A, member 3
Identifiers
Symbols OR3A3; OR17-137; OR17-16; OR17-201; OR3A6; OR3A7; OR3A8P
External IDs MGI3030245 HomoloGene74999 GeneCards: OR3A3 Gene
RNA expression pattern
PBB GE OR3A3 221426 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 8392 258704
Ensembl ENSG00000159961 ENSMUSG00000054406
UniProt P47888 n/a
RefSeq (mRNA) NM_012373 NM_146709.2
RefSeq (protein) NP_036505 NP_666920.2
Location (UCSC) Chr 17:
3.32 – 3.32 Mb
Chr 11:
74.16 – 74.17 Mb
PubMed search [1] [2]

Olfactory receptor 3A3 is a protein that in humans is encoded by the OR3A3 gene.[1][2][3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[3]

Contents

See also

References

  1. ^ Ben-Arie N, Lancet D, Taylor C, Khen M, Walker N, Ledbetter DH, Carrozzo R, Patel K et al. (Jul 1994). "Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire". Hum Mol Genet 3 (2): 229–35. doi:10.1093/hmg/3.2.229. PMID 8004088. 
  2. ^ Rouquier S, Taviaux S, Trask BJ, Brand-Arpon V, van den Engh G, Demaille J, Giorgi D (Mar 1998). "Distribution of olfactory receptor genes in the human genome". Nat Genet 18 (3): 243–50. doi:10.1038/ng0398-243. PMID 9500546. 
  3. ^ a b "Entrez Gene: OR3A3 olfactory receptor, family 3, subfamily A, member 3". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8392. 

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

Class II
(tetrapod specific receptors)

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