ZWINT

ZW10 interactor, also known as ZWINT, is a human gene.cite web | title = Entrez Gene: ZWINT ZW10 interactor| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11130| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.cite web | title = Entrez Gene: ZWINT ZW10 interactor| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11130| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Starr DA, Saffery R, Li Z, "et al." |title=HZwint-1, a novel human kinetochore component that interacts with HZW10. |journal=J. Cell. Sci. |volume=113 ( Pt 11) |issue= |pages= 1939–50 |year= 2000 |pmid= 10806105 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Musio A, Mariani T, Montagna C, "et al." |title=Recapitulation of the Roberts syndrome cellular phenotype by inhibition of INCENP, ZWINT-1 and ZW10 genes. |journal=Gene |volume=331 |issue= |pages= 33–40 |year= 2004 |pmid= 15094189 |doi= 10.1016/j.gene.2004.01.028
*cite journal | author=Cheeseman IM, Niessen S, Anderson S, "et al." |title=A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension. |journal=Genes Dev. |volume=18 |issue= 18 |pages= 2255–68 |year= 2004 |pmid= 15371340 |doi= 10.1101/gad.1234104
*cite journal | author=Wang H, Hu X, Ding X, "et al." |title=Human Zwint-1 specifies localization of Zeste White 10 to kinetochores and is essential for mitotic checkpoint signaling. |journal=J. Biol. Chem. |volume=279 |issue= 52 |pages= 54590–8 |year= 2005 |pmid= 15485811 |doi= 10.1074/jbc.M407588200
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Obuse C, Iwasaki O, Kiyomitsu T, "et al." |title=A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1. |journal=Nat. Cell Biol. |volume=6 |issue= 11 |pages= 1135–41 |year= 2004 |pmid= 15502821 |doi= 10.1038/ncb1187
*cite journal | author=Le XF, Lammayot A, Gold D, "et al." |title=Genes affecting the cell cycle, growth, maintenance, and drug sensitivity are preferentially regulated by anti-HER2 antibody through phosphatidylinositol 3-kinase-AKT signaling. |journal=J. Biol. Chem. |volume=280 |issue= 3 |pages= 2092–104 |year= 2005 |pmid= 15504738 |doi= 10.1074/jbc.M403080200
*cite journal | author=Kops GJ, Kim Y, Weaver BA, "et al." |title=ZW10 links mitotic checkpoint signaling to the structural kinetochore. |journal=J. Cell Biol. |volume=169 |issue= 1 |pages= 49–60 |year= 2005 |pmid= 15824131 |doi= 10.1083/jcb.200411118
*cite journal | author=Lin YT, Chen Y, Wu G, Lee WH |title=Hec1 sequentially recruits Zwint-1 and ZW10 to kinetochores for faithful chromosome segregation and spindle checkpoint control. |journal=Oncogene |volume=25 |issue= 52 |pages= 6901–14 |year= 2006 |pmid= 16732327 |doi= 10.1038/sj.onc.1209687

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