CBX2 (gene)

CBX2 (gene)
Chromobox homolog 2

PDB rendering based on 2d9u.
Identifiers
Symbols CBX2; CDCA6; M33; MGC10561
External IDs OMIM602770 MGI88289 HomoloGene7256 GeneCards: CBX2 Gene
RNA expression pattern
PBB GE CBX2 215989 at tn.png
PBB GE CBX2 gnf1h00861 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 84733 12416
Ensembl ENSG00000173894 ENSMUSG00000025577
UniProt Q14781 Q3TZG6
RefSeq (mRNA) NM_005189.2 NM_007623.2
RefSeq (protein) NP_005180.1 NP_031649.2
Location (UCSC) Chr 17:
77.75 – 77.76 Mb
Chr 11:
118.88 – 118.89 Mb
PubMed search [1] [2]

Chromobox protein homolog 2 is a protein that in humans is encoded by the CBX2 gene.[1][2][3] According to a New Scientist CBX2 controls human gender even more so than X/Y chromosomes[4].


Interactions

CBX2 (gene) has been shown to interact with RYBP.[5]

References

  1. ^ Gecz J, Gaunt SJ, Passage E, Burton RD, Cudrey C, Pearce JJ, Fontes M (Jul 1995). "Assignment of a Polycomb-like chromobox gene (CBX2) to human chromosome 17q25". Genomics 26 (1): 130–3. doi:10.1016/0888-7543(95)80091-Y. PMID 7782071. 
  2. ^ Chodak GW (Nov 1989). "Early detection and screening for prostatic cancer". Urology 34 (4 Suppl): 10–2; discussion 46–56. doi:10.1016/0090-4295(89)90228-8. PMID 2477932. 
  3. ^ "Entrez Gene: CBX2 chromobox homolog 2 (Pc class homolog, Drosophila)". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=84733. 
  4. ^ Ewen Callaway. "Girl with Y chromosome sheds light on maleness ", New Scientist, 2009-04-09. Retrieved on 2009-04-14.
  5. ^ García, E; Marcos-Gutiérrez C, del Mar Lorente M, Moreno J C, Vidal M (Jun. 1999). "RYBP, a new repressor protein that interacts with components of the mammalian Polycomb complex, and with the transcription factor YY1". EMBO J. (ENGLAND) 18 (12): 3404–18. doi:10.1093/emboj/18.12.3404. ISSN 0261-4189. PMC 1171420. PMID 10369680. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1171420. 

Further reading




Wikimedia Foundation. 2010.

Игры ⚽ Поможем сделать НИР

Look at other dictionaries:

  • Cromosoma 17 (humano) — Saltar a navegación, búsqueda El cromosoma 17 es uno de los 23 pares de cromosomas del ser humano. Normalmente se encuentran dos copias de este cromosoma. El cromosoma 17 se compone de más de 81 millones de pares bases (el material constitutivo… …   Wikipedia Español

  • Белки группы polycomb — (англ. Polycomb group proteins)  это семейство белков, которые способны ремоделировать хроматин. Впервые открыты у дрозофил.[1] Эти белки так видоизменяют структуру хроматина, что транскрипционные факторы не могут связываться с… …   Википедия

  • Female infertility — Classification and external resources ICD 10 N97.0 ICD 9 628 …   Wikipedia

  • Geschlechtsdetermination — Übergeordnet Reproduktions Entwicklungsprozess Untergeordnet Genetische/Somatische/Männliche/Weibliche/Primäre/Paarungstyp Geschlechsdetermination …   Deutsch Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”