- CBX2 (gene)
-
Chromobox protein homolog 2 is a protein that in humans is encoded by the CBX2 gene.[1][2][3] According to a New Scientist CBX2 controls human gender even more so than X/Y chromosomes[4].
Interactions
CBX2 (gene) has been shown to interact with RYBP.[5]
References
- ^ Gecz J, Gaunt SJ, Passage E, Burton RD, Cudrey C, Pearce JJ, Fontes M (Jul 1995). "Assignment of a Polycomb-like chromobox gene (CBX2) to human chromosome 17q25". Genomics 26 (1): 130–3. doi:10.1016/0888-7543(95)80091-Y. PMID 7782071.
- ^ Chodak GW (Nov 1989). "Early detection and screening for prostatic cancer". Urology 34 (4 Suppl): 10–2; discussion 46–56. doi:10.1016/0090-4295(89)90228-8. PMID 2477932.
- ^ "Entrez Gene: CBX2 chromobox homolog 2 (Pc class homolog, Drosophila)". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=84733.
- ^ Ewen Callaway. "Girl with Y chromosome sheds light on maleness ", New Scientist, 2009-04-09. Retrieved on 2009-04-14.
- ^ García, E; Marcos-Gutiérrez C, del Mar Lorente M, Moreno J C, Vidal M (Jun. 1999). "RYBP, a new repressor protein that interacts with components of the mammalian Polycomb complex, and with the transcription factor YY1". EMBO J. (ENGLAND) 18 (12): 3404–18. doi:10.1093/emboj/18.12.3404. ISSN 0261-4189. PMC 1171420. PMID 10369680. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1171420.
Further reading
- Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
- Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
- García E, Marcos-Gutiérrez C, del Mar Lorente M, et al. (1999). "RYBP, a new repressor protein that interacts with components of the mammalian Polycomb complex, and with the transcription factor YY1". EMBO J. 18 (12): 3404–18. doi:10.1093/emboj/18.12.3404. PMC 1171420. PMID 10369680. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1171420.
- Katoh-Fukui Y, Tsuchiya R, Shiroishi T, et al. (1998). "Male-to-female sex reversal in M33 mutant mice". Nature 393 (6686): 688–92. doi:10.1038/31482. PMID 9641679.
- Pearce JJ, Singh PB, Gaunt SJ (1992). "The mouse has a Polycomb-like chromobox gene". Development 114 (4): 921–9. PMID 1352241.
PDB gallery Categories:- Human proteins
- Chromosome 17 gene stubs
Wikimedia Foundation. 2010.