- PARP12
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Poly (ADP-ribose) polymerase family, member 12
PDB rendering based on 2pqf.Available structures PDB 2pqf Identifiers Symbols PARP12; FLJ22693; MST109; MSTP109; ZC3H1; ZC3HDC1 External IDs OMIM: 612481 MGI: 2143990 HomoloGene: 11236 GeneCards: PARP12 Gene EC number 2.4.2.30 Gene Ontology Molecular function • nucleic acid binding
• NAD+ ADP-ribosyltransferase activity
• zinc ion binding
• transferase activity
• metal ion bindingCellular component • nucleus Biological process • protein amino acid ADP-ribosylation Sources: Amigo / QuickGO RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 64761 243771 Ensembl ENSG00000059378 ENSMUSG00000038507 UniProt Q9H0J9 Q0VB94 RefSeq (mRNA) NM_022750 NM_172893.3 RefSeq (protein) NP_073587 NP_766481.2 Location (UCSC) Chr 7:
139.72 – 139.76 MbChr 6:
39.04 – 39.07 MbPubMed search [1] [2] Poly [ADP-ribose] polymerase 12 is an enzyme that in humans is encoded by the PARP12 gene.[1][2][3]
References
- ^ Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=311072.
- ^ Katoh M, Katoh M (Jul 2003). "Identification and characterization of human TIPARP gene within the CCNL amplicon at human chromosome 3q25.31". Int J Oncol 23 (2): 541–7. PMID 12851707.
- ^ "Entrez Gene: PARP12 poly (ADP-ribose) polymerase family, member 12". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64761.
Further reading
- Gerhard DS, Wagner L, Feingold EA et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928.
- Ota T, Suzuki Y, Nishikawa T et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Hillier LW, Fulton RS, Fulton LA et al. (2003). "The DNA sequence of human chromosome 7". Nature 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.
- Scherer SW, Cheung J, MacDonald JR et al. (2003). "Human Chromosome 7: DNA Sequence and Biology". Science 300 (5620): 767–72. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2882961.
- Strausberg RL, Feingold EA, Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
- <Please add first missing authors to populate metadata.> (1999). "Toward a complete human genome sequence". Genome Res. 8 (11): 1097–108. doi:10.1101/gr.8.11.1097. PMID 9847074.
PDB gallery Categories:- Human proteins
- Chromosome 7 gene stubs
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