MRPS25

Mitochondrial ribosomal protein S25, also known as MRPS25, is a human gene.cite web | title = Entrez Gene: MRPS25 mitochondrial ribosomal protein S25| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64432| accessdate = ]

PBB_Summary
section_title =
summary_text = Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. A pseudogene corresponding to this gene is found on chromosome 4.cite web | title = Entrez Gene: MRPS25 mitochondrial ribosomal protein S25| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64432| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Ewing RM, Chu P, Elisma F, "et al." |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Zhang Z, Gerstein M |title=Identification and characterization of over 100 mitochondrial ribosomal protein pseudogenes in the human genome. |journal=Genomics |volume=81 |issue= 5 |pages= 468-80 |year= 2003 |pmid= 12706105 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Kenmochi N, Suzuki T, Uechi T, "et al." |title=The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders. |journal=Genomics |volume=77 |issue= 1-2 |pages= 65-70 |year= 2001 |pmid= 11543634 |doi= 10.1006/geno.2001.6622
*cite journal | author=Cavdar Koc E, Burkhart W, Blackburn K, "et al." |title=The small subunit of the mammalian mitochondrial ribosome. Identification of the full complement of ribosomal proteins present. |journal=J. Biol. Chem. |volume=276 |issue= 22 |pages= 19363-74 |year= 2001 |pmid= 11279123 |doi= 10.1074/jbc.M100727200
*cite journal | author=Hattori A, Okumura K, Nagase T, "et al." |title=Characterization of long cDNA clones from human adult spleen. |journal=DNA Res. |volume=7 |issue= 6 |pages= 357-66 |year= 2001 |pmid= 11214971 |doi=
*cite journal | author=Koc EC, Burkhart W, Blackburn K, "et al." |title=A proteomics approach to the identification of mammalian mitochondrial small subunit ribosomal proteins. |journal=J. Biol. Chem. |volume=275 |issue= 42 |pages= 32585-91 |year= 2000 |pmid= 10938081 |doi= 10.1074/jbc.M003596200

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes