NVL (gene)

Nuclear VCP-like
Identifiers
Symbols	NVL;
External IDs	OMIM: 602426 MGI: 1914709 HomoloGene: 1902 GeneCards: NVL Gene
Gene Ontology Molecular function • nucleotide binding • ATP binding • nucleoside-triphosphatase activity Cellular component • nucleus • nucleolus • nucleolus • cytoplasm • aggresome Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	4931	67459
Ensembl	ENSG00000143748	ENSMUSG00000026516
UniProt	O15381	Q9CRW9
RefSeq (mRNA)	NM_002533.2	NM_026171.1
RefSeq (protein)	NP_002524.2	NP_080447.1
Location (UCSC)	Chr 1: 224.42 – 224.52 Mb	Chr 1: 183.02 – 183.07 Mb
PubMed search	[1]	[2]

Nuclear valosin-containing protein-like is a protein that in humans is encoded by the NVL gene.^[1][2]

References

1. ^ Germain-Lee EL, Obie C, Valle D (Nov 1997). "NVL: a new member of the AAA family of ATPases localized to the nucleus". Genomics 44 (1): 22–34. doi:10.1006/geno.1997.4856. PMID 9286697. 
2. ^ "Entrez Gene: NVL nuclear VCP-like". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4931. 

Further reading

• Nagahama M, Yamazoe T, Hara Y, et al. (2006). "The AAA-ATPase NVL2 is a component of pre-ribosomal particles that interacts with the DExD/H-box RNA helicase DOB1.". Biochem. Biophys. Res. Commun. 346 (3): 1075–82. doi:10.1016/j.bbrc.2006.06.017. PMID 16782053. 
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928. 
• Nagahama M, Hara Y, Seki A, et al. (2005). "NVL2 Is a Nucleolar AAA-ATPase that Interacts with Ribosomal Protein L5 through Its Nucleolar Localization Sequence". Mol. Biol. Cell 15 (12): 5712–23. doi:10.1091/mbc.E04-08-0692. PMC 532049. PMID 15469983. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=532049. 
• Leonard D, Ajuh P, Lamond AI, Legerski RJ (2003). "hLodestar/HuF2 interacts with CDC5L and is involved in pre-mRNA splicing". Biochem. Biophys. Res. Commun. 308 (4): 793–801. doi:10.1016/S0006-291X(03)01486-4. PMID 12927788. 
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241. 
• Scherl A, Couté Y, Déon C, et al. (2003). "Functional Proteomic Analysis of Human Nucleolus". Mol. Biol. Cell 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC 133617. PMID 12429849. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=133617. 
• Dias Neto E, Correa RG, Verjovski-Almeida S, et al. (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491–6. doi:10.1073/pnas.97.7.3491. PMC 16267. PMID 10737800. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=16267. 
• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.