NINJ1

Ninjurin 1
Identifiers
Symbols	NINJ1; NIN1; NINJURIN
External IDs	OMIM: 602062 HomoloGene: 88815 GeneCards: NINJ1 Gene
Gene Ontology Molecular function • protein binding Cellular component • membrane • integral to membrane Biological process • cell adhesion • nervous system development • tissue regeneration Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	4814	18081
Ensembl	ENSG00000131669	ENSMUSG00000037966
UniProt	Q92982	n/a
RefSeq (mRNA)	NM_004148	NM_013610.2
RefSeq (protein)	NP_004139	NP_038638.1
Location (UCSC)	Chr 9: 95.88 – 95.9 Mb	Chr 13: 49.28 – 49.29 Mb
PubMed search	[1]	[2]

Ninjurin-1 is a protein that in humans is encoded by the NINJ1 gene.^[1][2]

References

1. ^ Araki T, Milbrandt J (Oct 1996). "Ninjurin, a novel adhesion molecule, is induced by nerve injury and promotes axonal growth". Neuron 17 (2): 353–61. doi:10.1016/S0896-6273(00)80166-X. PMID 8780658. 
2. ^ "Entrez Gene: NINJ1 ninjurin 1". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4814. 

Further reading

• Guimarães PE, Fridman C, Gregório SP, et al. (2007). "WITHDRAWN: Association between polymorphisms in genes of inflammatory response and axonal repair with spinal cord injury.". Spinal Cord. doi:10.1038/sj.sc.3102122. PMID 17893696. 
• Cardoso CC, Martinez AN, Guimarães PE, et al. (2007). "Ninjurin 1 asp110ala single nucleotide polymorphism is associated with protection in leprosy nerve damage.". J. Neuroimmunol. 190 (1–2): 131–8. doi:10.1016/j.jneuroim.2007.07.015. PMID 17825431. 
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928. 
• Toyama T, Sasaki Y, Horimoto M, et al. (2005). "Ninjurin1 increases p21 expression and induces cellular senescence in human hepatoma cells". J. Hepatol. 41 (4): 637–43. doi:10.1016/j.jhep.2004.06.027. PMID 15464245. 
• Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature 429 (6990): 369–74. doi:10.1038/nature02465. PMC 2734081. PMID 15164053. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2734081. 
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241. 
• Chadwick BP, Heath SK, Williamson J, et al. (1998). "The human homologue of the ninjurin gene maps to the candidate region of hereditary sensory neuropathy type I (HSNI)". Genomics 47 (1): 58–63. doi:10.1006/geno.1997.5084. PMID 9465296. 
• Araki T, Zimonjic DB, Popescu NC, Milbrandt J (1997). "Mechanism of homophilic binding mediated by ninjurin, a novel widely expressed adhesion molecule". J. Biol. Chem. 272 (34): 21373–80. doi:10.1074/jbc.272.34.21373. PMID 9261151.