- NDUFC1
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NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa Identifiers Symbols NDUFC1; KFYI; MGC117464; MGC126847; MGC138266 External IDs OMIM: 603844 MGI: 1913627 HomoloGene: 1865 GeneCards: NDUFC1 Gene Gene Ontology Molecular function • NADH dehydrogenase (ubiquinone) activity Cellular component • mitochondrion
• mitochondrial inner membrane
• mitochondrial respiratory chain complex I
• membrane
• integral to membrane
• respiratory chainBiological process • mitochondrial electron transport, NADH to ubiquinone
• transport
• respiratory electron transport chainSources: Amigo / QuickGO RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 4717 66377 Ensembl ENSG00000109390 ENSMUSG00000037152 UniProt O43677 Q58DY9 RefSeq (mRNA) NM_001184986.1 NM_025523.1 RefSeq (protein) NP_001171915.1 NP_079799.1 Location (UCSC) Chr 4:
140.19 – 140.22 MbChr 3:
51.21 – 51.21 MbPubMed search [1] [2] NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial is an enzyme that in humans is encoded by the NDUFC1 gene.[1][2][3]
References
- ^ Ton C, Hwang DM, Dempsey AA, Liew CC (Jan 1998). "Identification and primary structure of five human NADH-ubiquinone oxidoreductase subunits". Biochem Biophys Res Commun 241 (2): 589–94. doi:10.1006/bbrc.1997.7707. PMID 9425316.
- ^ Emahazion T, Beskow A, Gyllensten U, Brookes AJ (Nov 1998). "Intron based radiation hybrid mapping of 15 complex I genes of the human electron transport chain". Cytogenet Cell Genet 82 (1–2): 115–9. doi:10.1159/000015082. PMID 9763677.
- ^ "Entrez Gene: NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4717.
Further reading
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
- Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=310934.
- Loeffen JL, Triepels RH, van den Heuvel LP, et al. (1999). "cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed". Biochem. Biophys. Res. Commun. 253 (2): 415–22. doi:10.1006/bbrc.1998.9786. PMID 9878551.
- Mao M, Fu G, Wu JS, et al. (1998). "Identification of genes expressed in human CD34(+) hematopoietic stem/progenitor cells by expressed sequence tags and efficient full-length cDNA cloning". Proc. Natl. Acad. Sci. U.S.A. 95 (14): 8175–80. doi:10.1073/pnas.95.14.8175. PMC 20949. PMID 9653160. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=20949.
Categories:- Human proteins
- Chromosome 4 gene stubs
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