Metanx

Metanx
Metanx
Combination of
L-methylfolate vitamin
Pyridoxal 5'-phosphate vitamin
Methylcobalamin vitamin
Clinical data
AHFS/Drugs.com monograph
Pregnancy cat.  ?
Legal status  ?
Identifiers
ATC code  ?
 N(what is this?)  (verify)

Metanx is a prescription medication made by Pamlab that contains L-methylfolate (vitamin B9), methylcobalamin (vitamin B12) and pyridoxal 5'-phosphate (vitamin B6). It is a vitamin B supplement.

It is indicated for the treatment of endothelial dysfunction and hyperhomocysteinemia. In particular it has been shown to be an effective treatment for diabetic peripheral neuropathy[1][2] and lower extremity ulcerations such as diabetic foot ulcers.[3]

Metanx contains the following active ingredients (per tablet):

  • L-methylfolate (Metafolin): 2.8 mg
  • Pyridoxal 5'-phosphate: 25 mg
  • Methylcobalamin: 2 mg

References

  1. ^ Vascular Disease Management 2 (Suppl 6): 1S-9S. 2005. 
  2. ^ Yaqub, Basim A, et al. (1992). "Effects of methylcobalamin on diabetic neuropathy". Clinical Neurology and Neurosurgery 94: 105–111. 
  3. ^ Boykin JV, Baylis C (2006). "Homocysteine--A Stealth Mediator of Impaired Wound Healing: A Preliminary Study". Wounds 18 (4): 101–116. 

External links