CD79B

CD79b molecule, immunoglobulin-associated beta, also known as CD79B (Cluster of Differentiation 79B), is a human gene.cite web | title = Entrez Gene: CD79B CD79b molecule, immunoglobulin-associated beta| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=974| accessdate = ]

PBB_Summary
section_title =
summary_text = The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-beta protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described.cite web | title = Entrez Gene: CD79B CD79b molecule, immunoglobulin-associated beta| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=974| accessdate = ]

ee also

* Cluster of differentiation

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Reth M |title=Antigen receptors on B lymphocytes. |journal=Annu. Rev. Immunol. |volume=10 |issue= |pages= 97–121 |year= 1992 |pmid= 1591006 |doi= 10.1146/annurev.iy.10.040192.000525
*cite journal | author=Müller B, Cooper L, Terhorst C |title=Cloning and sequencing of the cDNA encoding the human homologue of the murine immunoglobulin-associated protein B29. |journal=Eur. J. Immunol. |volume=22 |issue= 6 |pages= 1621–5 |year= 1992 |pmid= 1534761 |doi=
*cite journal | author=Lankester AC, van Schijndel GM, Cordell JL, "et al." |title=CD5 is associated with the human B cell antigen receptor complex. |journal=Eur. J. Immunol. |volume=24 |issue= 4 |pages= 812–6 |year= 1994 |pmid= 7512031 |doi=
*cite journal | author=Vasile S, Coligan JE, Yoshida M, Seon BK |title=Isolation and chemical characterization of the human B29 and mb-1 proteins of the B cell antigen receptor complex. |journal=Mol. Immunol. |volume=31 |issue= 6 |pages= 419–27 |year= 1994 |pmid= 7514267 |doi=
*cite journal | author=Brown VK, Ogle EW, Burkhardt AL, "et al." |title=Multiple components of the B cell antigen receptor complex associate with the protein tyrosine phosphatase, CD45. |journal=J. Biol. Chem. |volume=269 |issue= 25 |pages= 17238–44 |year= 1994 |pmid= 7516335 |doi=
*cite journal | author=Rowley RB, Burkhardt AL, Chao HG, "et al." |title=Syk protein-tyrosine kinase is regulated by tyrosine-phosphorylated Ig alpha/Ig beta immunoreceptor tyrosine activation motif binding and autophosphorylation. |journal=J. Biol. Chem. |volume=270 |issue= 19 |pages= 11590–4 |year= 1995 |pmid= 7538118 |doi=
*cite journal | author=Pani G, Kozlowski M, Cambier JC, "et al." |title=Identification of the tyrosine phosphatase PTP1C as a B cell antigen receptor-associated protein involved in the regulation of B cell signaling. |journal=J. Exp. Med. |volume=181 |issue= 6 |pages= 2077–84 |year= 1995 |pmid= 7539038 |doi=
*cite journal | author=Müller B, Cooper L, Terhorst C |title=Interplay between the human TCR/CD3 epsilon and the B-cell antigen receptor associated Ig-beta (B29). |journal=Immunol. Lett. |volume=44 |issue= 2-3 |pages= 97–103 |year= 1995 |pmid= 7541024 |doi=
*cite journal | author=Saouaf SJ, Kut SA, Fargnoli J, "et al." |title=Reconstitution of the B cell antigen receptor signaling components in COS cells. |journal=J. Biol. Chem. |volume=270 |issue= 45 |pages= 27072–8 |year= 1995 |pmid= 7592958 |doi=
*cite journal | author=Hashimoto S, Chiorazzi N, Gregersen PK |title=Alternative splicing of CD79a (Ig-alpha/mb-1) and CD79b (Ig-beta/B29) RNA transcripts in human B cells. |journal=Mol. Immunol. |volume=32 |issue= 9 |pages= 651–9 |year= 1995 |pmid= 7643857 |doi=
*cite journal | author=Hashimoto S, Chiorazzi N, Gregersen PK |title=The complete sequence of the human CD79b (Ig beta/B29) gene: identification of a conserved exon/intron organization, immunoglobulin-like regulatory regions, and allelic polymorphism. |journal=Immunogenetics |volume=40 |issue= 2 |pages= 145–9 |year= 1994 |pmid= 7913081 |doi=
*cite journal | author=Gold MR, Chiu R, Ingham RJ, "et al." |title=Activation and serine phosphorylation of the p56lck protein tyrosine kinase in response to antigen receptor cross-linking in B lymphocytes. |journal=J. Immunol. |volume=153 |issue= 6 |pages= 2369–80 |year= 1994 |pmid= 8077654 |doi=
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Hashimoto S, Gregersen PK, Chiorazzi N |title=The human Ig-beta cDNA sequence, a homologue of murine B29, is identical in B cell and plasma cell lines producing all the human Ig isotypes. |journal=J. Immunol. |volume=150 |issue= 2 |pages= 491–8 |year= 1993 |pmid= 8419481 |doi=
*cite journal | author=Wood WJ, Thompson AA, Korenberg J, "et al." |title=Isolation and chromosomal mapping of the human immunoglobulin-associated B29 gene (IGB). |journal=Genomics |volume=16 |issue= 1 |pages= 187–92 |year= 1993 |pmid= 8486355 |doi= 10.1006/geno.1993.1157
*cite journal | author=Thompson AA, Wood WJ, Gilly MJ, "et al." |title=The promoter and 5' flanking sequences controlling human B29 gene expression. |journal=Blood |volume=87 |issue= 2 |pages= 666–73 |year= 1996 |pmid= 8555489 |doi=
*cite journal | author=Astsaturov IA, Matutes E, Morilla R, "et al." |title=Differential expression of B29 (CD79b) and mb-1 (CD79a) proteins in acute lymphoblastic leukaemia. |journal=Leukemia |volume=10 |issue= 5 |pages= 769–73 |year= 1996 |pmid= 8656670 |doi=
*cite journal | author=Koyama M, Nakamura T, Higashihara M, "et al." |title=The novel variants of mb-1 and B29 transcripts generated by alternative mRNA splicing. |journal=Immunol. Lett. |volume=47 |issue= 3 |pages= 151–6 |year= 1996 |pmid= 8747711 |doi=
*cite journal | author=Carter RH, Doody GM, Bolen JB, Fearon DT |title=Membrane IgM-induced tyrosine phosphorylation of CD19 requires a CD19 domain that mediates association with components of the B cell antigen receptor complex. |journal=J. Immunol. |volume=158 |issue= 7 |pages= 3062–9 |year= 1997 |pmid= 9120258 |doi=

External links

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