PDLIM3

PDZ and LIM domain 3
PDB rendering based on 1v5l.
Available structures PDB 1v5l
Identifiers
Symbols	PDLIM3; ALP; DKFZp686L0362; FLJ26096
External IDs	OMIM: 605889 HomoloGene: 8710 GeneCards: PDLIM3 Gene
Gene Ontology Molecular function • cytoskeletal protein binding • zinc ion binding • structural constituent of muscle • metal ion binding Cellular component • cytoplasm • actin cytoskeleton • sarcomere Biological process • actin filament organization • heart development Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	27295	n/a
Ensembl	ENSG00000154553	n/a
UniProt	Q53GG5	n/a
RefSeq (mRNA)	NM_001114107.3	n/a
RefSeq (protein)	NP_001107579.1	n/a
Location (UCSC)	Chr 4: 186.42 – 186.46 Mb	n/a
PubMed search	[1]	n/a

PDZ and LIM domain protein 3 is a protein that in humans is encoded by the PDLIM3 gene.^[1][2][3]

References

1. ^ Bouju S, Pietu G, Le Cunff M, Cros N, Malzac P, Pellissier JF, Pons F, Leger JJ, Auffray C, Dechesne CA (May 1999). "Exclusion of muscle specific actinin-associated LIM protein (ALP) gene from 4q35 facioscapulohumeral muscular dystrophy (FSHD) candidate genes". Neuromuscul Disord 9 (1): 3–10. doi:10.1016/S0960-8966(98)00087-X. PMID 10063829. 
2. ^ Pietu G, Alibert O, Guichard V, Lamy B, Bois F, Leroy E, Mariage-Sampson R, Houlgatte R, Soularue P, Auffray C (Dec 1996). "Novel gene transcripts preferentially expressed in human muscles revealed by quantitative hybridization of a high density cDNA array". Genome Res 6 (6): 492–503. doi:10.1101/gr.6.6.492. PMID 8828038. 
3. ^ "Entrez Gene: PDLIM3 PDZ and LIM domain 3". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=27295. 

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298. 
• Xia H, Winokur ST, Kuo WL et al. (1997). "Actinin-associated LIM Protein: Identification of a Domain Interaction between PDZ and Spectrin-like Repeat Motifs". J. Cell Biol. 139 (2): 507–15. doi:10.1083/jcb.139.2.507. PMC 2139795. PMID 9334352. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2139795. 
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149. 
• Strausberg RL, Feingold EA, Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241. 
• Klaavuniemi T, Kelloniemi A, Ylänne J (2004). "The ZASP-like motif in actinin-associated LIM protein is required for interaction with the alpha-actinin rod and for targeting to the muscle Z-line". J. Biol. Chem. 279 (25): 26402–10. doi:10.1074/jbc.M401871200. PMID 15084604. 
• Gerhard DS, Wagner L, Feingold EA et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928. 
• Brown AK, O'Connor PJ, Roberts TE et al. (2006). "Ultrasonography for rheumatologists: the development of specific competency based educational outcomes". Ann. Rheum. Dis. 65 (5): 629–36. doi:10.1136/ard.2005.039974. PMC 1798129. PMID 16192291. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1798129. 
• Arola AM, Sanchez X, Murphy RT et al. (2007). "Mutations in PDLIM3 and MYOZ1 encoding myocyte Z line proteins are infrequently found in idiopathic dilated cardiomyopathy". Mol. Genet. Metab. 90 (4): 435–40. doi:10.1016/j.ymgme.2006.12.008. PMID 17254821.