Buffer base

Buffer base

Buffer base (BB) is the sum of all buffering agents in the blood.[1] It is possible to state its value indirectly by this equation: BB = (Na++K+)-(Cl-). It is used in blood test to estimate acid-base physiology in individuals.

Normal blood values are around 48 mmol/l [2].

Normal buffer base

Normal buffer base (NBB) is what the buffer base would have been at normal pH (7.4), normal PCO2[3] (40 mmHg) and normal temperature (37 Celsius) [4].

The content of hemoglobin in blood increases this value. The correlation is:

NBB = 41.7+0.68×Hb

, where Hb is in mmol/l.[4] A normal value of this is ~9.3 mmol/l, making the normal blood value of NBB 48 mmol/l.

References

  1. ^ medical-dictionary.thefreedictionary.com
  2. ^ iv-partner.com - Acid-Base Balance
  3. ^ anst.uu.se Some notes on human acid-base physiology
  4. ^ a b freepatentsonline.com Method and apparatus for pH recording. United States Patent 4384586



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