Dehydrogenase/reductase (SDR family) member 3
Symbols DHRS3; RDH17; Rsdr1; SDR1; SDR16C1; retSDR1
External IDs OMIM612830 MGI1315215 HomoloGene20994 GeneCards: DHRS3 Gene
EC number
RNA expression pattern
PBB GE DHRS3 202481 at tn.png
More reference expression data
Species Human Mouse
Entrez 9249 20148
Ensembl ENSG00000162496 ENSMUSG00000066026
UniProt O75911 O88876
RefSeq (mRNA) NM_004753 NM_011303
RefSeq (protein) NP_004744 NP_035433
Location (UCSC) Chr 1:
12.63 – 12.68 Mb
Chr 4:
144.48 – 144.52 Mb
PubMed search [1] [2]

Short-chain dehydrogenase/reductase 3 is an enzyme that in humans is encoded by the DHRS3 gene.[1][2][3][4]


  1. ^ Haeseleer F, Huang J, Lebioda L, Saari JC, Palczewski K (Sep 1998). "Molecular characterization of a novel short-chain dehydrogenase/reductase that reduces all-trans-retinal". J Biol Chem 273 (34): 21790–9. doi:10.1074/jbc.273.34.21790. PMID 9705317. 
  2. ^ Haeseleer F, Jang GF, Imanishi Y, Driessen CA, Matsumura M, Nelson PS, Palczewski K (Nov 2002). "Dual-substrate Specificity Short Chain Retinol Dehydrogenases from the Vertebrate Retina". J Biol Chem 277 (47): 45537–46. doi:10.1074/jbc.M208882200. PMC 1435693. PMID 12226107. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1435693. 
  3. ^ Persson B, Kallberg Y, Bray JE, Bruford E, Dellaporta SL, Favia AD, Duarte RG, Jornvall H, Kavanagh KL, Kedishvili N, Kisiela M, Maser E, Mindnich R, Orchard S, Penning TM, Thornton JM, Adamski J, Oppermann U (Feb 2009). "The SDR (Short-Chain Dehydrogenase/Reductase and Related Enzymes) Nomenclature Initiative". Chem Biol Interact 178 (1–3): 94–8. doi:10.1016/j.cbi.2008.10.040. PMC 2896744. PMID 19027726. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2896744. 
  4. ^ "Entrez Gene: DHRS3 dehydrogenase/reductase (SDR family) member 3". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9249. 

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  • Short-chain dehydrogenase — Pfam box Symbol = adh short Name = short chain dehydrogenase width = caption = Pfam= PF00106 InterPro= IPR002198 SMART= PROSITE = PDOC00060 SCOP = 1hdc TCDB = OPM family= 127 OPM protein= 1xu7 PDB=PDB3|1edoA:78 246 PDB3|1zbqA:10 183 PDB3|1gz6A:10 …   Wikipedia

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