NOL8

Nucleolar protein 8
Identifiers
Symbols	NOL8; C9orf34; DKFZp686P12242; FLJ20736; Nop132; bA62C3.3; bA62C3.4
External IDs	OMIM: 611534 MGI: 1918180 HomoloGene: 41210 GeneCards: NOL8 Gene
Gene Ontology Molecular function • nucleotide binding • RNA binding • protein binding Cellular component • nucleus • nucleolus Biological process • DNA replication • positive regulation of cell growth Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	55035	70930
Ensembl	ENSG00000198000	ENSMUSG00000021392
UniProt	Q76FK4	Q059P5
RefSeq (mRNA)	NM_017948.5	NM_001081350.1
RefSeq (protein)	NP_060418	NP_001074819.1
Location (UCSC)	Chr 9: 95.06 – 95.09 Mb	Chr 13: 49.75 – 49.77 Mb
PubMed search	[1]	[2]

Nucleolar protein 8 is a protein that in humans is encoded by the NOL8 gene.^[1][2]

Interactions

NOL8 has been shown to interact with RRAGA^[3] and NIP7.^[3]

References

1. ^ Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci USA 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241. 
2. ^ "Entrez Gene: NOL8 nucleolar protein 8". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55035. 
3. ^ ^{a b} Sekiguchi, Takeshi; Todaka Yuko, Wang Yonggang, Hirose Eiji, Nakashima Nobutaka, Nishimoto Takeharu (Feb. 2004). "A novel human nucleolar protein, Nop132, binds to the G proteins, RRAG A/C/D". J. Biol. Chem. (United States) 279 (9): 8343–50. doi:10.1074/jbc.M305935200. ISSN 0021-9258. PMID 14660641. 

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298. 
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149. 
• Sekiguchi T, Hirose E, Nakashima N, et al. (2001). "Novel G proteins, Rag C and Rag D, interact with GTP-binding proteins, Rag A and Rag B.". J. Biol. Chem. 276 (10): 7246–57. doi:10.1074/jbc.M004389200. PMID 11073942. 
• Sekiguchi T, Todaka Y, Wang Y, et al. (2004). "A novel human nucleolar protein, Nop132, binds to the G proteins, RRAG A/C/D.". J. Biol. Chem. 279 (9): 8343–50. doi:10.1074/jbc.M305935200. PMID 14660641. 
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
• Jinawath N, Furukawa Y, Nakamura Y (2004). "Identification of NOL8, a nucleolar protein containing an RNA recognition motif (RRM), which was overexpressed in diffuse-type gastric cancer.". Cancer Sci. 95 (5): 430–5. doi:10.1111/j.1349-7006.2004.tb03227.x. PMID 15132771. 
• Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9.". Nature 429 (6990): 369–74. doi:10.1038/nature02465. PMC 2734081. PMID 15164053. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2734081. 
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928. 
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.