Deoxythymidylate kinase (thymidylate kinase)

PDB rendering based on 1e2d.
Symbols DTYMK; CDC8; FLJ44192; MGC198617; PP3731; TMPK; TYMK
External IDs OMIM188345 MGI108396 HomoloGene6285 GeneCards: DTYMK Gene
EC number
Species Human Mouse
Entrez 1841 21915
Ensembl ENSG00000168393 ENSMUSG00000026281
UniProt P23919 P97930
RefSeq (mRNA) NM_001165031.1 NM_023136
RefSeq (protein) NP_001158503.1 NP_075625
Location (UCSC) Chr 2:
242.62 – 242.63 Mb
Chr 1:
95.69 – 95.7 Mb
PubMed search [1] [2]

Thymidylate kinase also known as deoxythymidylate kinase or dTMP kinase is an enzyme that in humans is encoded by the DTYMK gene.[1][2][3] and belongs to thymidylate kinase family of proteins.


  1. ^ Su JY, Sclafani RA (May 1991). "Molecular cloning and expression of the human deoxythymidylate kinase gene in yeast". Nucleic Acids Res 19 (4): 823–7. doi:10.1093/nar/19.4.823. PMC 333717. PMID 2017365. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=333717. 
  2. ^ Huang SH, Tang A, Drisco B, Zhang SQ, Seeger R, Li C, Jong A (Aug 1994). "Human dTMP kinase: gene expression and enzymatic activity coinciding with cell cycle progression and cell growth". DNA Cell Biol 13 (5): 461–71. doi:10.1089/dna.1994.13.461. PMID 8024690. 
  3. ^ "Entrez Gene: DTYMK deoxythymidylate kinase (thymidylate kinase)". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1841. 

Further reading