CYB561

Cytochrome b-561
Identifiers
Symbols	CYB561; FRRS2
External IDs	OMIM: 600019 MGI: 103253 HomoloGene: 37552 GeneCards: CYB561 Gene
Gene Ontology Molecular function • ferric-chelate reductase activity • cytochrome-b5 reductase activity • metal ion binding Cellular component • integral to plasma membrane • membrane Biological process • generation of precursor metabolites and energy • transport • electron transport chain Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	1534	13056
Ensembl	ENSG00000008283	ENSMUSG00000019590
UniProt	P49447	Q8CE89
RefSeq (mRNA)	NM_001017916.1	NM_007805.4
RefSeq (protein)	NP_001017916.1	NP_031831.2
Location (UCSC)	Chr 17: 61.51 – 61.52 Mb	Chr 11: 105.8 – 105.81 Mb
PubMed search	[1]	[2]

Cytochrome b561 is a protein that in humans is encoded by the CYB561 gene.^[1][2]

References

1. ^ McBride OW, Yi HF, Srivastava M (Nov 1994). "The human cytochrome b561 gene (CYB561) is located at 17q11-qter". Genomics 21 (3): 662–3. doi:10.1006/geno.1994.1332. PMID 7959749. 
2. ^ "Entrez Gene: CYB561 cytochrome b-561". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1534. 

Further reading

• Duong LT, Fleming PJ (1982). "Isolation and properties of cytochrome b561 from bovine adrenal chromaffin granules.". J. Biol. Chem. 257 (15): 8561–4. PMID 7096323. 
• Srivastava M (1995). "Genomic structure and expression of the human gene encoding cytochrome b561, an integral protein of the chromaffin granule membrane.". J. Biol. Chem. 270 (39): 22714–20. doi:10.1074/jbc.270.39.22714. PMID 7559396. 
• Srivastava M, Gibson KR, Pollard HB, Fleming PJ (1994). "Human cytochrome b561: a revised hypothesis for conformation in membranes which reconciles sequence and functional information". Biochem. J. 303 ( Pt 3) (Pt 3): 915–21. PMC 1137633. PMID 7980462. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1137633. 
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241. 
• Bashtovyy D, Bérczi A, Asard H, Páli T (2004). "Structure prediction for the di-heme cytochrome b561 protein family". Protoplasma 221 (1–2): 31–40. doi:10.1007/s00709-002-0065-0. PMID 12768339. 
• Kang MK, Kameta A, Shin KH, et al. (2003). "Senescence-associated genes in normal human oral keratinocytes". Exp. Cell Res. 287 (2): 272–81. doi:10.1016/S0014-4827(03)00061-2. PMID 12837283. 
• Vargas JD, Herpers B, McKie AT, et al. (2003). "Stromal cell-derived receptor 2 and cytochrome b561 are functional ferric reductases". Biochim. Biophys. Acta 1651 (1–2): 116–23. PMID 14499595. 
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928.