PTPRO

Protein tyrosine phosphatase, receptor type, O, also known as PTPRO, is a human gene.cite web | title = Entrez Gene: PTPRO protein tyrosine phosphatase, receptor type, O| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5800| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a receptor-type protein tyrosine phosphatase containing a single intracellular catalytic domain with a characteristic signature motif. The gene product, which has a transmembrane domain, is an integral membrane protein. Several alternatively spliced transcript variants, some of which encode different isoforms of the protein, have been described. These variants exhibit tissue-specific expression.cite web | title = Entrez Gene: PTPRO protein tyrosine phosphatase, receptor type, O| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5800| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Thomas PE, Wharram BL, Goyal M, "et al." |title=GLEPP1, a renal glomerular epithelial cell (podocyte) membrane protein-tyrosine phosphatase. Identification, molecular cloning, and characterization in rabbit. |journal=J. Biol. Chem. |volume=269 |issue= 31 |pages= 19953–62 |year= 1994 |pmid= 7519601 |doi=
*cite journal | author=Wiggins RC, Wiggins JE, Goyal M, "et al." |title=Molecular cloning of cDNAs encoding human GLEPP1, a membrane protein tyrosine phosphatase: characterization of the GLEPP1 protein distribution in human kidney and assignment of the GLEPP1 gene to human chromosome 12p12-p13. |journal=Genomics |volume=27 |issue= 1 |pages= 174–81 |year= 1995 |pmid= 7665166 |doi= 10.1006/geno.1995.1021
*cite journal | author=Seimiya H, Sawabe T, Inazawa J, Tsuruo T |title=Cloning, expression and chromosomal localization of a novel gene for protein tyrosine phosphatase (PTP-U2) induced by various differentiation-inducing agents. |journal=Oncogene |volume=10 |issue= 9 |pages= 1731–8 |year= 1995 |pmid= 7753550 |doi=
*cite journal | author=Feito MJ, Bragardo M, Buonfiglio D, "et al." |title=gp 120s derived from four syncytium-inducing HIV-1 strains induce different patterns of CD4 association with lymphocyte surface molecules. |journal=Int. Immunol. |volume=9 |issue= 8 |pages= 1141–7 |year= 1997 |pmid= 9263011 |doi=
*cite journal | author=Avraham S, London R, Tulloch GA, "et al." |title=Characterization and chromosomal localization of PTPRO, a novel receptor protein tyrosine phosphatase, expressed in hematopoietic stem cells. |journal=Gene |volume=204 |issue= 1-2 |pages= 5–16 |year= 1998 |pmid= 9434160 |doi=
*cite journal | author=Taniguchi Y, London R, Schinkmann K, "et al." |title=The receptor protein tyrosine phosphatase, PTP-RO, is upregulated during megakaryocyte differentiation and Is associated with the c-Kit receptor. |journal=Blood |volume=94 |issue= 2 |pages= 539–49 |year= 1999 |pmid= 10397721 |doi=
*cite journal | author=Aguiar RC, Yakushijin Y, Kharbanda S, "et al." |title=PTPROt: an alternatively spliced and developmentally regulated B-lymphoid phosphatase that promotes G0/G1 arrest. |journal=Blood |volume=94 |issue= 7 |pages= 2403–13 |year= 1999 |pmid= 10498613 |doi=
*cite journal | author=Wang Z, Bhattacharya N, Meyer MK, "et al." |title=Pim-1 negatively regulates the activity of PTP-U2S phosphatase and influences terminal differentiation and apoptosis of monoblastoid leukemia cells. |journal=Arch. Biochem. Biophys. |volume=390 |issue= 1 |pages= 9–18 |year= 2001 |pmid= 11368509 |doi= 10.1006/abbi.2001.2370
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Motiwala T, Kutay H, Ghoshal K, "et al." |title=Protein tyrosine phosphatase receptor-type O (PTPRO) exhibits characteristics of a candidate tumor suppressor in human lung cancer. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 38 |pages= 13844–9 |year= 2004 |pmid= 15356345 |doi= 10.1073/pnas.0405451101
*cite journal | author=Chen L, Juszczynski P, Takeyama K, "et al." |title=Protein tyrosine phosphatase receptor-type O truncated (PTPROt) regulates SYK phosphorylation, proximal B-cell-receptor signaling, and cellular proliferation. |journal=Blood |volume=108 |issue= 10 |pages= 3428–33 |year= 2007 |pmid= 16888096 |doi= 10.1182/blood-2006-03-013821
*cite journal | author=Motiwala T, Majumder S, Kutay H, "et al." |title=Methylation and silencing of protein tyrosine phosphatase receptor type O in chronic lymphocytic leukemia. |journal=Clin. Cancer Res. |volume=13 |issue= 11 |pages= 3174–81 |year= 2007 |pmid= 17545520 |doi= 10.1158/1078-0432.CCR-06-1720
*cite journal | author=Tian J, Wang HP, Mao YY, "et al." |title=Reduced glomerular epithelial protein 1 expression and podocyte injury in immunoglobulin A nephropathy. |journal=J. Int. Med. Res. |volume=35 |issue= 3 |pages= 338–45 |year= 2007 |pmid= 17593862 |doi=

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