PTPN14

Protein tyrosine phosphatase, non-receptor type 14, also known as PTPN14, is a human gene.cite web | title = Entrez Gene: PTPN14 protein tyrosine phosphatase, non-receptor type 14| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5784| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. The specific function of this PTP has not yet been determined.cite web | title = Entrez Gene: PTPN14 protein tyrosine phosphatase, non-receptor type 14| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5784| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Gyapay G, Morissette J, Vignal A, "et al." |title=The 1993-94 Généthon human genetic linkage map. |journal=Nat. Genet. |volume=7 |issue= 2 Spec No |pages= 246–339 |year= 1994 |pmid= 7545953 |doi= 10.1038/ng0694supp-246
*cite journal | author=Smith AL, Mitchell PJ, Shipley J, "et al." |title=Pez: a novel human cDNA encoding protein tyrosine phosphatase- and ezrin-like domains. |journal=Biochem. Biophys. Res. Commun. |volume=209 |issue= 3 |pages= 959–65 |year= 1995 |pmid= 7733990 |doi= 10.1006/bbrc.1995.1591
*cite journal | author=Ogata M, Takada T, Mori Y, "et al." |title=Effects of overexpression of PTP36, a putative protein tyrosine phosphatase, on cell adhesion, cell growth, and cytoskeletons in HeLa cells. |journal=J. Biol. Chem. |volume=274 |issue= 18 |pages= 12905–9 |year= 1999 |pmid= 10212280 |doi=
*cite journal | author=Ogata M, Takada T, Mori Y, "et al." |title=Regulation of phosphorylation level and distribution of PTP36, a putative protein tyrosine phosphatase, by cell-substrate adhesion. |journal=J. Biol. Chem. |volume=274 |issue= 29 |pages= 20717–24 |year= 1999 |pmid= 10400706 |doi=
*cite journal | author=Aoyama K, Matsuda T, Aoki N |title=Characterization of newly identified four isoforms for a putative cytosolic protein tyrosine phosphatase PTP36. |journal=Biochem. Biophys. Res. Commun. |volume=266 |issue= 2 |pages= 523–31 |year= 2000 |pmid= 10600535 |doi= 10.1006/bbrc.1999.1845
*cite journal | author=Wadham C, Gamble JR, Vadas MA, Khew-Goodall Y |title=Translocation of protein tyrosine phosphatase Pez/PTPD2/PTP36 to the nucleus is associated with induction of cell proliferation. |journal=J. Cell. Sci. |volume=113 ( Pt 17) |issue= |pages= 3117–23 |year= 2000 |pmid= 10934049 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Wadham C, Gamble JR, Vadas MA, Khew-Goodall Y |title=The protein tyrosine phosphatase Pez is a major phosphatase of adherens junctions and dephosphorylates beta-catenin. |journal=Mol. Biol. Cell |volume=14 |issue= 6 |pages= 2520–9 |year= 2004 |pmid= 12808048 |doi= 10.1091/mbc.E02-09-0577
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Jin J, Smith FD, Stark C, "et al." |title=Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization. |journal=Curr. Biol. |volume=14 |issue= 16 |pages= 1436–50 |year= 2004 |pmid= 15324660 |doi= 10.1016/j.cub.2004.07.051
*cite journal | author=Barr AJ, Debreczeni JE, Eswaran J, Knapp S |title=Crystal structure of human protein tyrosine phosphatase 14 (PTPN14) at 1.65-A resolution. |journal=Proteins |volume=63 |issue= 4 |pages= 1132–6 |year= 2006 |pmid= 16534812 |doi= 10.1002/prot.20958
*cite journal | author=Olsen JV, Blagoev B, Gnad F, "et al." |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026

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