PTPN3

Protein tyrosine phosphatase, non-receptor type 3, also known as PTPN3, is a human gene.cite web | title = Entrez Gene: PTPN3 protein tyrosine phosphatase, non-receptor type 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5774| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. P97, a cell cycle regulator involved in a variety of membrane related functions, has been shown to be a substrate of this PTP. This PTP was also found to interact with, and be regulated by adaptor protein 14-3-3 beta.cite web | title = Entrez Gene: PTPN3 protein tyrosine phosphatase, non-receptor type 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5774| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Arimura Y, Hinoda Y, Itoh F, "et al." |title=cDNA cloning of new protein tyrosine phosphatases in the human colon. |journal=Tumour Biol. |volume=13 |issue= 3 |pages= 180–6 |year= 1992 |pmid= 1626183 |doi=
*cite journal | author=Yang Q, Tonks NK |title=Isolation of a cDNA clone encoding a human protein-tyrosine phosphatase with homology to the cytoskeletal-associated proteins band 4.1, ezrin, and talin. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=88 |issue= 14 |pages= 5949–53 |year= 1991 |pmid= 1648725 |doi=
*cite journal | author=Ikuta S, Itoh F, Hinoda Y, "et al." |title=Expression of cytoskeletal-associated protein tyrosine phosphatase PTPH1 mRNA in human hepatocellular carcinoma. |journal=J. Gastroenterol. |volume=29 |issue= 6 |pages= 727–32 |year= 1995 |pmid= 7874267 |doi=
*cite journal | author=Itoh F, Ikuta S, Hinoda Y, "et al." |title=Expression and chromosomal assignment of PTPH1 gene encoding a cytosolic protein tyrosine phosphatase homologous to cytoskeletal-associated proteins. |journal=Int. J. Cancer |volume=55 |issue= 6 |pages= 947–51 |year= 1994 |pmid= 8253532 |doi=
*cite journal | author=Zhang SH, Kobayashi R, Graves PR, "et al." |title=Serine phosphorylation-dependent association of the band 4.1-related protein-tyrosine phosphatase PTPH1 with 14-3-3beta protein. |journal=J. Biol. Chem. |volume=272 |issue= 43 |pages= 27281–7 |year= 1997 |pmid= 9341175 |doi=
*cite journal | author=Zhang SH, Liu J, Kobayashi R, Tonks NK |title=Identification of the cell cycle regulator VCP (p97/CDC48) as a substrate of the band 4.1-related protein-tyrosine phosphatase PTPH1. |journal=J. Biol. Chem. |volume=274 |issue= 25 |pages= 17806–12 |year= 1999 |pmid= 10364224 |doi=
*cite journal | author=Gjörloff-Wingren A, Saxena M, Han S, "et al." |title=Subcellular localization of intracellular protein tyrosine phosphatases in T cells. |journal=Eur. J. Immunol. |volume=30 |issue= 8 |pages= 2412–21 |year= 2000 |pmid= 10940933 |doi=
*cite journal | author=Zheng Y, Schlondorff J, Blobel CP |title=Evidence for regulation of the tumor necrosis factor alpha-convertase (TACE) by protein-tyrosine phosphatase PTPH1. |journal=J. Biol. Chem. |volume=277 |issue= 45 |pages= 42463–70 |year= 2003 |pmid= 12207026 |doi= 10.1074/jbc.M207459200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Sozio MS, Mathis MA, Young JA, "et al." |title=PTPH1 is a predominant protein-tyrosine phosphatase capable of interacting with and dephosphorylating the T cell receptor zeta subunit. |journal=J. Biol. Chem. |volume=279 |issue= 9 |pages= 7760–9 |year= 2004 |pmid= 14672952 |doi= 10.1074/jbc.M309994200
*cite journal | author=Blanchetot C, Chagnon M, Dubé N, "et al." |title=Substrate-trapping techniques in the identification of cellular PTP targets. |journal=Methods |volume=35 |issue= 1 |pages= 44–53 |year= 2005 |pmid= 15588985 |doi= 10.1016/j.ymeth.2004.07.007
*cite journal | author=Benzinger A, Muster N, Koch HB, "et al." |title=Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer. |journal=Mol. Cell Proteomics |volume=4 |issue= 6 |pages= 785–95 |year= 2005 |pmid= 15778465 |doi= 10.1074/mcp.M500021-MCP200
*cite journal | author=Jespersen T, Gavillet B, van Bemmelen MX, "et al." |title=Cardiac sodium channel Na(v)1.5 interacts with and is regulated by the protein tyrosine phosphatase PTPH1. |journal=Biochem. Biophys. Res. Commun. |volume=348 |issue= 4 |pages= 1455–62 |year= 2006 |pmid= 16930557 |doi= 10.1016/j.bbrc.2006.08.014
*cite journal | author=Jing M, Bohl J, Brimer N, "et al." |title=Degradation of tyrosine phosphatase PTPN3 (PTPH1) by association with oncogenic human papillomavirus E6 proteins. |journal=J. Virol. |volume=81 |issue= 5 |pages= 2231–9 |year= 2007 |pmid= 17166906 |doi= 10.1128/JVI.01979-06
*cite journal | author=Töpffer S, Müller-Schiffmann A, Matentzoglu K, "et al." |title=Protein tyrosine phosphatase H1 is a target of the E6 oncoprotein of high-risk genital human papillomaviruses. |journal=J. Gen. Virol. |volume=88 |issue= Pt 11 |pages= 2956–65 |year= 2007 |pmid= 17947517 |doi= 10.1099/vir.0.83123-0

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