CDH16

Cadherin 16, KSP-cadherin, also known as CDH16, is a human gene.cite web | title = Entrez Gene: CDH16 cadherin 16, KSP-cadherin| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1014| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development.cite web | title = Entrez Gene: CDH16 cadherin 16, KSP-cadherin| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1014| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Thomson RB, Igarashi P, Biemesderfer D, "et al." |title=Isolation and cDNA cloning of Ksp-cadherin, a novel kidney-specific member of the cadherin multigene family. |journal=J. Biol. Chem. |volume=270 |issue= 29 |pages= 17594–601 |year= 1995 |pmid= 7615566 |doi=
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Thomson RB, Ward DC, Quaggin SE, "et al." |title=cDNA cloning and chromosomal localization of the human and mouse isoforms of Ksp-cadherin. |journal=Genomics |volume=51 |issue= 3 |pages= 445–51 |year= 1998 |pmid= 9721215 |doi= 10.1006/geno.1998.5402
*cite journal | author=Thomson RB, Aronson PS |title=Immunolocalization of Ksp-cadherin in the adult and developing rabbit kidney. |journal=Am. J. Physiol. |volume=277 |issue= 1 Pt 2 |pages= F146–56 |year= 1999 |pmid= 10409308 |doi=
*cite journal | author=Baudry D, Jeanpierre C |title=Assignment of E-cadherin (CDH1) and KSP-cadherin (CDH16) to chromosome 16q22.1 by radiation hybrid mapping. |journal=Cytogenet. Cell Genet. |volume=88 |issue= 3-4 |pages= 253–4 |year= 2000 |pmid= 10828602 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Thomson RB, Mentone S, Kim R, "et al." |title=Histopathological analysis of renal cystic epithelia in the Pkd2WS25/- mouse model of ADPKD. |journal=Am. J. Physiol. Renal Physiol. |volume=285 |issue= 5 |pages= F870–80 |year= 2003 |pmid= 12851251 |doi= 10.1152/ajprenal.00153.2003
*cite journal | author=Clark HF, Gurney AL, Abaya E, "et al." |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265–70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003
*cite journal | author=Wendeler MW, Praus M, Jung R, "et al." |title=Ksp-cadherin is a functional cell-cell adhesion molecule related to LI-cadherin. |journal=Exp. Cell Res. |volume=294 |issue= 2 |pages= 345–55 |year= 2004 |pmid= 15023525 |doi= 10.1016/j.yexcr.2003.11.022
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Hishikawa K, Marumo T, Miura S, "et al." |title=Leukemia inhibitory factor induces multi-lineage differentiation of adult stem-like cells in kidney via kidney-specific cadherin 16. |journal=Biochem. Biophys. Res. Commun. |volume=328 |issue= 1 |pages= 288–91 |year= 2005 |pmid= 15670782 |doi= 10.1016/j.bbrc.2004.12.167
*cite journal | author=Thedieck C, Kuczyk M, Klingel K, "et al." |title=Expression of Ksp-cadherin during kidney development and in renal cell carcinoma. |journal=Br. J. Cancer |volume=92 |issue= 11 |pages= 2010–7 |year= 2005 |pmid= 15886705 |doi= 10.1038/sj.bjc.6602597
*cite journal | author=Kuehn A, Paner GP, Skinnider BF, "et al." |title=Expression analysis of kidney-specific cadherin in a wide spectrum of traditional and newly recognized renal epithelial neoplasms: diagnostic and histogenetic implications. |journal=Am. J. Surg. Pathol. |volume=31 |issue= 10 |pages= 1528–33 |year= 2007 |pmid= 17895753 |doi= 10.1097/PAS.0b013e318058818c

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