- LMO4
LIM domain only 4, also known as LMO4, is a human
gene .cite web | title = Entrez Gene: LMO4 LIM domain only 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8543| accessdate = ]PBB_Summary
section_title =
summary_text = LIM domain only 4 is a cysteine-rich, two LIM domain-containing protein that may play a role as a transcriptional regulator or possibly an oncogene. Its mRNA is characterized by a GC-rich 5' region and by multiple ATTT motifs in the 3' region. A variant transcript missing a portion of the 5' region has been identified but cannot be confirmed because of the GC-rich nature of the region.cite web | title = Entrez Gene: LMO4 LIM domain only 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8543| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Kenny DA, Jurata LW, Saga Y, Gill GN |title=Identification and characterization of LMO4, an LMO gene with a novel pattern of expression during embryogenesis. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 19 |pages= 11257–62 |year= 1998 |pmid= 9736723 |doi=
*cite journal | author=Racevskis J, Dill A, Sparano JA, Ruan H |title=Molecular cloning of LMO41, a new human LIM domain gene. |journal=Biochim. Biophys. Acta |volume=1445 |issue= 1 |pages= 148–53 |year= 1999 |pmid= 10209267 |doi=
*cite journal | author=Tse E, Grutz G, Garner AA, "et al." |title=Characterization of the Lmo4 gene encoding a LIM-only protein: genomic organization and comparative chromosomal mapping. |journal=Mamm. Genome |volume=10 |issue= 11 |pages= 1089–94 |year= 2000 |pmid= 10556429 |doi=
*cite journal | author=Sum EY, Peng B, Yu X, "et al." |title=The LIM domain protein LMO4 interacts with the cofactor CtIP and the tumor suppressor BRCA1 and inhibits BRCA1 activity. |journal=J. Biol. Chem. |volume=277 |issue= 10 |pages= 7849–56 |year= 2002 |pmid= 11751867 |doi= 10.1074/jbc.M110603200
*cite journal | author=Deane JE, Visvader JE, Mackay JP, Matthew JM |title=1H, 15N and 13C assignments of FLIN4, an intramolecular LMO4:ldb1 complex. |journal=J. Biomol. NMR |volume=23 |issue= 2 |pages= 165–6 |year= 2003 |pmid= 12153047 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Vu D, Marin P, Walzer C, "et al." |title=Transcription regulator LMO4 interferes with neuritogenesis in human SH-SY5Y neuroblastoma cells. |journal=Brain Res. Mol. Brain Res. |volume=115 |issue= 2 |pages= 93–103 |year= 2003 |pmid= 12877980 |doi=
*cite journal | author=Manetopoulos C, Hansson A, Karlsson J, "et al." |title=The LIM-only protein LMO4 modulates the transcriptional activity of HEN1. |journal=Biochem. Biophys. Res. Commun. |volume=307 |issue= 4 |pages= 891–9 |year= 2003 |pmid= 12878195 |doi=
*cite journal | author=Sutherland KD, Visvader JE, Choong DY, "et al." |title=Mutational analysis of the LMO4 gene, encoding a BRCA1-interacting protein, in breast carcinomas. |journal=Int. J. Cancer |volume=107 |issue= 1 |pages= 155–8 |year= 2003 |pmid= 12925972 |doi= 10.1002/ijc.11343
*cite journal | author=Colland F, Jacq X, Trouplin V, "et al." |title=Functional proteomics mapping of a human signaling pathway. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1324–32 |year= 2004 |pmid= 15231748 |doi= 10.1101/gr.2334104
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Novotny-Diermayr V, Lin B, Gu L, Cao X |title=Modulation of the interleukin-6 receptor subunit glycoprotein 130 complex and its signaling by LMO4 interaction. |journal=J. Biol. Chem. |volume=280 |issue= 13 |pages= 12747–57 |year= 2005 |pmid= 15677447 |doi= 10.1074/jbc.M500175200
*cite journal | author=Sun T, Patoine C, Abu-Khalil A, "et al." |title=Early asymmetry of gene transcription in embryonic human left and right cerebral cortex. |journal=Science |volume=308 |issue= 5729 |pages= 1794–8 |year= 2005 |pmid= 15894532 |doi= 10.1126/science.1110324
*cite journal | author=Sum EY, Segara D, Duscio B, "et al." |title=Overexpression of LMO4 induces mammary hyperplasia, promotes cell invasion, and is a predictor of poor outcome in breast cancer. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=102 |issue= 21 |pages= 7659–64 |year= 2005 |pmid= 15897450 |doi= 10.1073/pnas.0502990102
*cite journal | author=Jeffries CM, Graham SC, Stokes PH, "et al." |title=Stabilization of a binary protein complex by intein-mediated cyclization. |journal=Protein Sci. |volume=15 |issue= 11 |pages= 2612–8 |year= 2007 |pmid= 17001033 |doi= 10.1110/ps.062377006PBB_Controls
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