DPYSL3

Dihydropyrimidinase-like 3
Identifiers
Symbols	DPYSL3; CRMP-4; CRMP4; DRP-3; DRP3; LCRMP; ULIP; ULIP-1
External IDs	OMIM: 601168 MGI: 1349762 HomoloGene: 20361 GeneCards: DPYSL3 Gene
Gene Ontology Molecular function • dihydropyrimidinase activity Cellular component • cytoplasm • cytosol • growth cone • cell projection Biological process • nucleobase, nucleoside, nucleotide and nucleic acid metabolic process • pyrimidine base catabolic process • signal transduction • nervous system development • axon guidance Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	1809	22240
Ensembl	ENSG00000113657	ENSMUSG00000024501
UniProt	Q14195	Q3TAS8
RefSeq (mRNA)	NM_001197294.1	NM_009468
RefSeq (protein)	NP_001184223.1	NP_033494
Location (UCSC)	Chr 5: 146.77 – 146.89 Mb	Chr 18: 43.48 – 43.6 Mb
PubMed search	[1]	[2]

Dihydropyrimidinase-related protein 3 is an enzyme that in humans is encoded by the DPYSL3 gene.^[1][2][3]

References

1. ^ Hamajima N, Matsuda K, Sakata S, Tamaki N, Sasaki M, Nonaka M (Jan 1997). "A novel gene family defined by human dihydropyrimidinase and three related proteins with differential tissue distribution". Gene 180 (1-2): 157–63. doi:10.1016/S0378-1119(96)00445-3. PMID 8973361. 
2. ^ Gaetano C, Matsuo T, Thiele CJ (Jun 1997). "Identification and characterization of a retinoic acid-regulated human homologue of the unc-33-like phosphoprotein gene (hUlip) from neuroblastoma cells". J Biol Chem 272 (18): 12195–201. doi:10.1074/jbc.272.18.12195. PMID 9115293. 
3. ^ "Entrez Gene: DPYSL3 dihydropyrimidinase-like 3". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1809. 

Further reading

• Dawson SJ, White LA (1992). "Treatment of Haemophilus aphrophilus endocarditis with ciprofloxacin.". J. Infect. 24 (3): 317–20. doi:10.1016/S0163-4453(05)80037-4. PMID 1602151. 
• Inagaki H, Kato Y, Hamajima N, et al. (2000). "Differential expression of dihydropyrimidinase-related protein genes in developing and adult enteric nervous system.". Histochem. Cell Biol. 113 (1): 37–41. doi:10.1007/s004180050005. PMID 10664068. 
• Matsuo T, Stauffer JK, Walker RL, et al. (2000). "Structure and promoter analysis of the human unc-33-like phosphoprotein gene. E-box required for maximal expression in neuroblastoma and myoblasts.". J. Biol. Chem. 275 (22): 16560–8. doi:10.1074/jbc.M001312200. PMID 10748015. 
• Fukada M, Watakabe I, Yuasa-Kawada J, et al. (2001). "Molecular characterization of CRMP5, a novel member of the collapsin response mediator protein family.". J. Biol. Chem. 275 (48): 37957–65. doi:10.1074/jbc.M003277200. PMID 10956643. 
• Weitzdoerfer R, Fountoulakis M, Lubec G (2002). "Aberrant expression of dihydropyrimidinase related proteins-2,-3 and -4 in fetal Down syndrome brain.". J. Neural Transm. Suppl. (61): 95–107. PMID 11771764. 
• Franken S, Junghans U, Rosslenbroich V, et al. (2003). "Collapsin response mediator proteins of neonatal rat brain interact with chondroitin sulfate.". J. Biol. Chem. 278 (5): 3241–50. doi:10.1074/jbc.M210181200. PMID 12444086. 
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241. 
• Rosslenbroich V, Dai L, Franken S, et al. (2003). "Subcellular localization of collapsin response mediator proteins to lipid rafts.". Biochem. Biophys. Res. Commun. 305 (2): 392–9. doi:10.1016/S0006-291X(03)00754-X. PMID 12745088. 
• Ballif BA, Villén J, Beausoleil SA, et al. (2005). "Phosphoproteomic analysis of the developing mouse brain.". Mol. Cell Proteomics 3 (11): 1093–101. doi:10.1074/mcp.M400085-MCP200. PMID 15345747. 
• Choi YL, Kim CJ, Matsuo T, et al. (2005). "HUlip, a human homologue of unc-33-like phosphoprotein of Caenorhabditis elegans; Immunohistochemical localization in the developing human brain and patterns of expression in nervous system tumors.". J. Neurooncol. 73 (1): 19–27. doi:10.1007/s11060-004-3013-3. PMID 15933812. 
• Cole AR, Causeret F, Yadirgi G, et al. (2006). "Distinct priming kinases contribute to differential regulation of collapsin response mediator proteins by glycogen synthase kinase-3 in vivo.". J. Biol. Chem. 281 (24): 16591–8. doi:10.1074/jbc.M513344200. PMC 1805471. PMID 16611631. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1805471. 
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.