SEMA3B

Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B, also known as SEMA3B, is a human gene.cite web | title = Entrez Gene: SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7869| accessdate = ]

PBB_Summary
section_title =
summary_text = The semaphorin/collapsin family of molecules plays a critical role in the guidance of growth cones during neuronal development. The secreted protein encoded by this gene family member is important in axonal guidance and has been shown to act as a tumor suppressor by inducing apoptosis.cite web | title = Entrez Gene: SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7869| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Püschel AW, Adams RH, Betz H |title=Murine semaphorin D/collapsin is a member of a diverse gene family and creates domains inhibitory for axonal extension. |journal=Neuron |volume=14 |issue= 5 |pages= 941–8 |year= 1995 |pmid= 7748561 |doi=
*cite journal | author=Wei MH, Latif F, Bader S, "et al." |title=Construction of a 600-kilobase cosmid clone contig and generation of a transcriptional map surrounding the lung cancer tumor suppressor gene (TSG) locus on human chromosome 3p21.3: progress toward the isolation of a lung cancer TSG. |journal=Cancer Res. |volume=56 |issue= 7 |pages= 1487–92 |year= 1996 |pmid= 8603390 |doi=
*cite journal | author=Sekido Y, Bader S, Latif F, "et al." |title=Human semaphorins A(V) and IV reside in the 3p21.3 small cell lung cancer deletion region and demonstrate distinct expression patterns. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=93 |issue= 9 |pages= 4120–5 |year= 1996 |pmid= 8633026 |doi=
*cite journal | author=Takahashi T, Nakamura F, Jin Z, "et al." |title=Semaphorins A and E act as antagonists of neuropilin-1 and agonists of neuropilin-2 receptors. |journal=Nat. Neurosci. |volume=1 |issue= 6 |pages= 487–93 |year= 1999 |pmid= 10196546 |doi= 10.1038/2203
*cite journal | author=Lerman MI, Minna JD |title=The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium. |journal=Cancer Res. |volume=60 |issue= 21 |pages= 6116–33 |year= 2000 |pmid= 11085536 |doi=
*cite journal | author=Tomizawa Y, Sekido Y, Kondo M, "et al." |title=Inhibition of lung cancer cell growth and induction of apoptosis after reexpression of 3p21.3 candidate tumor suppressor gene SEMA3B. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=98 |issue= 24 |pages= 13954–9 |year= 2002 |pmid= 11717452 |doi= 10.1073/pnas.231490898
*cite journal | author=Tse C, Xiang RH, Bracht T, Naylor SL |title=Human Semaphorin 3B (SEMA3B) located at chromosome 3p21.3 suppresses tumor formation in an adenocarcinoma cell line. |journal=Cancer Res. |volume=62 |issue= 2 |pages= 542–6 |year= 2002 |pmid= 11809707 |doi=
*cite journal | author=Ochi K, Mori T, Toyama Y, "et al." |title=Identification of semaphorin3B as a direct target of p53. |journal=Neoplasia |volume=4 |issue= 1 |pages= 82–7 |year= 2002 |pmid= 11922394 |doi= 10.1038/sj/neo/7900211
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Kuroki T, Trapasso F, Yendamuri S, "et al." |title=Allelic loss on chromosome 3p21.3 and promoter hypermethylation of semaphorin 3B in non-small cell lung cancer. |journal=Cancer Res. |volume=63 |issue= 12 |pages= 3352–5 |year= 2003 |pmid= 12810670 |doi=
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Castro-Rivera E, Ran S, Thorpe P, Minna JD |title=Semaphorin 3B (SEMA3B) induces apoptosis in lung and breast cancer, whereas VEGF165 antagonizes this effect. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 31 |pages= 11432–7 |year= 2004 |pmid= 15273288 |doi= 10.1073/pnas.0403969101
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Marsit CJ, Wiencke JK, Liu M, Kelsey KT |title=The race associated allele of Semaphorin 3B (SEMA3B) T415I and its role in lung cancer in African-Americans and Latino-Americans. |journal=Carcinogenesis |volume=26 |issue= 8 |pages= 1446–9 |year= 2005 |pmid= 15831529 |doi= 10.1093/carcin/bgi098
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Nair PN, McArdle L, Cornell J, "et al." |title=High-resolution analysis of 3p deletion in neuroblastoma and differential methylation of the SEMA3B tumor suppressor gene. |journal=Cancer Genet. Cytogenet. |volume=174 |issue= 2 |pages= 100–10 |year= 2007 |pmid= 17452250 |doi= 10.1016/j.cancergencyto.2006.11.017

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