KCNK9

Potassium channel, subfamily K, member 9, also known as KCNK9, is a human gene.cite web | title = Entrez Gene: KCNK9 potassium channel, subfamily K, member 9| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51305| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. This open channel is highly expressed in the cerebellum. It is inhibited by extracellular acidification and arachidonic acid, and strongly inhibited by phorbol 12-myristate 13-acetate.cite web | title = Entrez Gene: KCNK9 potassium channel, subfamily K, member 9| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51305| accessdate = ]

ee also

* Tandem pore domain potassium channel

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Goldstein SA, Bockenhauer D, O'Kelly I, Zilberberg N |title=Potassium leak channels and the KCNK family of two-P-domain subunits. |journal=Nat. Rev. Neurosci. |volume=2 |issue= 3 |pages= 175–84 |year= 2001 |pmid= 11256078 |doi=
*cite journal | author=Goldstein SA, Bayliss DA, Kim D, "et al." |title=International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels. |journal=Pharmacol. Rev. |volume=57 |issue= 4 |pages= 527–40 |year= 2006 |pmid= 16382106 |doi= 10.1124/pr.57.4.12
*cite journal | author=Kim Y, Bang H, Kim D |title=TASK-3, a new member of the tandem pore K(+) channel family. |journal=J. Biol. Chem. |volume=275 |issue= 13 |pages= 9340–7 |year= 2000 |pmid= 10734076 |doi=
*cite journal | author=Rajan S, Wischmeyer E, Xin Liu G, "et al." |title=TASK-3, a novel tandem pore domain acid-sensitive K+ channel. An extracellular histiding as pH sensor. |journal=J. Biol. Chem. |volume=275 |issue= 22 |pages= 16650–7 |year= 2000 |pmid= 10747866 |doi= 10.1074/jbc.M000030200
*cite journal | author=Chapman CG, Meadows HJ, Godden RJ, "et al." |title=Cloning, localisation and functional expression of a novel human, cerebellum specific, two pore domain potassium channel. |journal=Brain Res. Mol. Brain Res. |volume=82 |issue= 1-2 |pages= 74–83 |year= 2001 |pmid= 11042359 |doi=
*cite journal | author=Vega-Saenz de Miera E, Lau DH, Zhadina M, "et al." |title=KT3.2 and KT3.3, two novel human two-pore K(+) channels closely related to TASK-1. |journal=J. Neurophysiol. |volume=86 |issue= 1 |pages= 130–42 |year= 2001 |pmid= 11431495 |doi=
*cite journal | author=Talley EM, Bayliss DA |title=Modulation of TASK-1 (Kcnk3) and TASK-3 (Kcnk9) potassium channels: volatile anesthetics and neurotransmitters share a molecular site of action. |journal=J. Biol. Chem. |volume=277 |issue= 20 |pages= 17733–42 |year= 2002 |pmid= 11886861 |doi= 10.1074/jbc.M200502200
*cite journal | author=Rajan S, Preisig-Müller R, Wischmeyer E, "et al." |title=Interaction with 14-3-3 proteins promotes functional expression of the potassium channels TASK-1 and TASK-3. |journal=J. Physiol. (Lond.) |volume=545 |issue= Pt 1 |pages= 13–26 |year= 2003 |pmid= 12433946 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Mu D, Chen L, Zhang X, "et al." |title=Genomic amplification and oncogenic properties of the KCNK9 potassium channel gene. |journal=Cancer Cell |volume=3 |issue= 3 |pages= 297–302 |year= 2003 |pmid= 12676587 |doi=
*cite journal | author=Pei L, Wiser O, Slavin A, "et al." |title=Oncogenic potential of TASK3 (Kcnk9) depends on K+ channel function. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 13 |pages= 7803–7 |year= 2003 |pmid= 12782791 |doi= 10.1073/pnas.1232448100
*cite journal | author=Rusznák Z, Pocsai K, Kovács I, "et al." |title=Differential distribution of TASK-1, TASK-2 and TASK-3 immunoreactivities in the rat and human cerebellum. |journal=Cell. Mol. Life Sci. |volume=61 |issue= 12 |pages= 1532–42 |year= 2004 |pmid= 15197476 |doi= 10.1007/s00018-004-4082-3
*cite journal | author=Clarke CE, Veale EL, Green PJ, "et al." |title=Selective block of the human 2-P domain potassium channel, TASK-3, and the native leak potassium current, IKSO, by zinc. |journal=J. Physiol. (Lond.) |volume=560 |issue= Pt 1 |pages= 51–62 |year= 2005 |pmid= 15284350 |doi= 10.1113/jphysiol.2004.070292
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Kim CJ, Cho YG, Jeong SW, "et al." |title=Altered expression of KCNK9 in colorectal cancers. |journal=APMIS |volume=112 |issue= 9 |pages= 588–94 |year= 2005 |pmid= 15601307 |doi= 10.1111/j.1600-0463.2004.apm1120905.x
*cite journal | author=Pocsai K, Kosztka L, Bakondi G, "et al." |title=Melanoma cells exhibit strong intracellular TASK-3-specific immunopositivity in both tissue sections and cell culture. |journal=Cell. Mol. Life Sci. |volume=63 |issue= 19-20 |pages= 2364–76 |year= 2006 |pmid= 17013562 |doi= 10.1007/s00018-006-6166-8
*cite journal | author=Zuzarte M, Rinné S, Schlichthörl G, "et al." |title=A di-acidic sequence motif enhances the surface expression of the potassium channel TASK-3. |journal=Traffic |volume=8 |issue= 8 |pages= 1093–100 |year= 2007 |pmid= 17547699 |doi= 10.1111/j.1600-0854.2007.00593.x

External links

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