- RHOQ
Ras homolog gene family, member Q, also known as RHOQ, is a human
gene .cite web | title = Entrez Gene: RHOQ ras homolog gene family, member Q| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23433| accessdate = ]PBB_Summary
section_title =
summary_text = TC10 is a member of the RAS superfamily of small GTP-binding proteins (see HRAS, MIM 190020) involved in insulin-stimulated glucose uptake. [supplied by OMIM] cite web | title = Entrez Gene: RHOQ ras homolog gene family, member Q| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23433| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Drivas GT, Shih A, Coutavas E, "et al." |title=Characterization of four novel ras-like genes expressed in a human teratocarcinoma cell line. |journal=Mol. Cell. Biol. |volume=10 |issue= 4 |pages= 1793–8 |year= 1990 |pmid= 2108320 |doi=
*cite journal | author=Murphy GA, Solski PA, Jillian SA, "et al." |title=Cellular functions of TC10, a Rho family GTPase: regulation of morphology, signal transduction and cell growth. |journal=Oncogene |volume=18 |issue= 26 |pages= 3831–45 |year= 1999 |pmid= 10445846 |doi= 10.1038/sj.onc.1202758
*cite journal | author=Joberty G, Perlungher RR, Macara IG |title=The Borgs, a new family of Cdc42 and TC10 GTPase-interacting proteins. |journal=Mol. Cell. Biol. |volume=19 |issue= 10 |pages= 6585–97 |year= 2000 |pmid= 10490598 |doi=
*cite journal | author=Joberty G, Petersen C, Gao L, Macara IG |title=The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42. |journal=Nat. Cell Biol. |volume=2 |issue= 8 |pages= 531–9 |year= 2000 |pmid= 10934474 |doi= 10.1038/35019573
*cite journal | author=Vignal E, De Toledo M, Comunale F, "et al." |title=Characterization of TCL, a new GTPase of the rho family related to TC10 andCcdc42. |journal=J. Biol. Chem. |volume=275 |issue= 46 |pages= 36457–64 |year= 2000 |pmid= 10967094 |doi= 10.1074/jbc.M003487200
*cite journal | author=Michaelson D, Silletti J, Murphy G, "et al." |title=Differential localization of Rho GTPases in live cells: regulation by hypervariable regions and RhoGDI binding. |journal=J. Cell Biol. |volume=152 |issue= 1 |pages= 111–26 |year= 2001 |pmid= 11149925 |doi=
*cite journal | author=Neudauer CL, Joberty G, Macara IG |title=PIST: a novel PDZ/coiled-coil domain binding partner for the rho-family GTPase TC10. |journal=Biochem. Biophys. Res. Commun. |volume=280 |issue= 2 |pages= 541–7 |year= 2001 |pmid= 11162552 |doi= 10.1006/bbrc.2000.4160
*cite journal | author=Chiang SH, Hou JC, Hwang J, "et al." |title=Cloning and functional characterization of related TC10 isoforms, a subfamily of Rho proteins involved in insulin-stimulated glucose transport. |journal=J. Biol. Chem. |volume=277 |issue= 15 |pages= 13067–73 |year= 2002 |pmid= 11821390 |doi= 10.1074/jbc.M109471200
*cite journal | author=Kanzaki M, Watson RT, Hou JC, "et al." |title=Small GTP-binding protein TC10 differentially regulates two distinct populations of filamentous actin in 3T3L1 adipocytes. |journal=Mol. Biol. Cell |volume=13 |issue= 7 |pages= 2334–46 |year= 2003 |pmid= 12134073 |doi= 10.1091/mbc.01-10-0490
*cite journal | author=Chang L, Adams RD, Saltiel AR |title=The TC10-interacting protein CIP4/2 is required for insulin-stimulated Glut4 translocation in 3T3L1 adipocytes. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 20 |pages= 12835–40 |year= 2002 |pmid= 12242347 |doi= 10.1073/pnas.202495599
*cite journal | author=Abe T, Kato M, Miki H, "et al." |title=Small GTPase Tc10 and its homologue RhoT induce N-WASP-mediated long process formation and neurite outgrowth. |journal=J. Cell. Sci. |volume=116 |issue= Pt 1 |pages= 155–68 |year= 2003 |pmid= 12456725 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Heilig R, Eckenberg R, Petit JL, "et al." |title=The DNA sequence and analysis of human chromosome 14. |journal=Nature |volume=421 |issue= 6923 |pages= 601–7 |year= 2003 |pmid= 12508121 |doi= 10.1038/nature01348
*cite journal | author=Watson RT, Furukawa M, Chiang SH, "et al." |title=The exocytotic trafficking of TC10 occurs through both classical and nonclassical secretory transport pathways in 3T3L1 adipocytes. |journal=Mol. Cell. Biol. |volume=23 |issue= 3 |pages= 961–74 |year= 2003 |pmid= 12529401 |doi=
*cite journal | author=Inoue M, Chang L, Hwang J, "et al." |title=The exocyst complex is required for targeting of Glut4 to the plasma membrane by insulin. |journal=Nature |volume=422 |issue= 6932 |pages= 629–33 |year= 2003 |pmid= 12687004 |doi= 10.1038/nature01533
*cite journal | author=Chunqiu Hou J, Pessin JE |title=Lipid Raft targeting of the TC10 amino terminal domain is responsible for disruption of adipocyte cortical actin. |journal=Mol. Biol. Cell |volume=14 |issue= 9 |pages= 3578–91 |year= 2004 |pmid= 12972548 |doi= 10.1091/mbc.E03-01-0012
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Ng Y, Tan I, Lim L, Leung T |title=Expression of the human myotonic dystrophy kinase-related Cdc42-binding kinase gamma is regulated by promoter DNA methylation and Sp1 binding. |journal=J. Biol. Chem. |volume=279 |issue= 33 |pages= 34156–64 |year= 2004 |pmid= 15194684 |doi= 10.1074/jbc.M405252200
*cite journal | author=Ruusala A, Aspenström P |title=Isolation and characterisation of DOCK8, a member of the DOCK180-related regulators of cell morphology. |journal=FEBS Lett. |volume=572 |issue= 1-3 |pages= 159–66 |year= 2004 |pmid= 15304341 |doi= 10.1016/j.febslet.2004.06.095
*cite journal | author=Nalbant P, Hodgson L, Kraynov V, "et al." |title=Activation of endogenous Cdc42 visualized in living cells. |journal=Science |volume=305 |issue= 5690 |pages= 1615–9 |year= 2004 |pmid= 15361624 |doi= 10.1126/science.1100367PBB_Controls
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