- AKAP9
A kinase (PRKA) anchor protein (yotiao) 9, also known as AKAP9, is a human
gene .cite web | title = Entrez Gene: AKAP9 A kinase (PRKA) anchor protein (yotiao) 9| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10142| accessdate = ]PBB_Summary
section_title =
summary_text = The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternate splicing of this gene results in many isoforms that localize to the centrosome and the Golgi apparatus, and interact with numerous signaling proteins from multiple signal transduction pathways. These signaling proteins include type II protein kinase A, serine/threonine kinase protein kinase N, protein phosphatase 1, protein phosphatase 2a, protein kinase C-epsilon and phosphodiesterase 4D3.cite web | title = Entrez Gene: AKAP9 A kinase (PRKA) anchor protein (yotiao) 9| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10142| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Lin JW, Wyszynski M, Madhavan R, "et al." |title=Yotiao, a novel protein of neuromuscular junction and brain that interacts with specific splice variants of NMDA receptor subunit NR1. |journal=J. Neurosci. |volume=18 |issue= 6 |pages= 2017–27 |year= 1998 |pmid= 9482789 |doi=
*cite journal | author=Nagase T, Ishikawa K, Suyama M, "et al." |title=Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=5 |issue= 5 |pages= 277–86 |year= 1999 |pmid= 9872452 |doi=
*cite journal | author=Schmidt PH, Dransfield DT, Claudio JO, "et al." |title=AKAP350, a multiply spliced protein kinase A-anchoring protein associated with centrosomes. |journal=J. Biol. Chem. |volume=274 |issue= 5 |pages= 3055–66 |year= 1999 |pmid= 9915845 |doi=
*cite journal | author=Witczak O, Skålhegg BS, Keryer G, "et al." |title=Cloning and characterization of a cDNA encoding an A-kinase anchoring protein located in the centrosome, AKAP450. |journal=EMBO J. |volume=18 |issue= 7 |pages= 1858–68 |year= 1999 |pmid= 10202149 |doi= 10.1093/emboj/18.7.1858
*cite journal | author=Takahashi M, Shibata H, Shimakawa M, "et al." |title=Characterization of a novel giant scaffolding protein, CG-NAP, that anchors multiple signaling enzymes to centrosome and the golgi apparatus. |journal=J. Biol. Chem. |volume=274 |issue= 24 |pages= 17267–74 |year= 1999 |pmid= 10358086 |doi=
*cite journal | author=Westphal RS, Tavalin SJ, Lin JW, "et al." |title=Regulation of NMDA receptors by an associated phosphatase-kinase signaling complex. |journal=Science |volume=285 |issue= 5424 |pages= 93–6 |year= 1999 |pmid= 10390370 |doi=
*cite journal | author=Husi H, Ward MA, Choudhary JS, "et al." |title=Proteomic analysis of NMDA receptor-adhesion protein signaling complexes. |journal=Nat. Neurosci. |volume=3 |issue= 7 |pages= 661–9 |year= 2000 |pmid= 10862698 |doi= 10.1038/76615
*cite journal | author=Takahashi M, Mukai H, Oishi K, "et al." |title=Association of immature hypophosphorylated protein kinase cepsilon with an anchoring protein CG-NAP. |journal=J. Biol. Chem. |volume=275 |issue= 44 |pages= 34592–6 |year= 2000 |pmid= 10945988 |doi= 10.1074/jbc.M005285200
*cite journal | author=Marx SO, Kurokawa J, Reiken S, "et al." |title=Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel. |journal=Science |volume=295 |issue= 5554 |pages= 496–9 |year= 2002 |pmid= 11799244 |doi= 10.1126/science.1066843
*cite journal | author=Steadman BT, Schmidt PH, Shanks RA, "et al." |title=Transforming acidic coiled-coil-containing protein 4 interacts with centrosomal AKAP350 and the mitotic spindle apparatus. |journal=J. Biol. Chem. |volume=277 |issue= 33 |pages= 30165–76 |year= 2002 |pmid= 12015314 |doi= 10.1074/jbc.M201914200
*cite journal | author=Bray JD, Chennathukuzhi VM, Hecht NB |title=Identification and characterization of cDNAs encoding four novel proteins that interact with translin associated factor-X. |journal=Genomics |volume=79 |issue= 6 |pages= 799–808 |year= 2002 |pmid= 12036294 |doi= 10.1006/geno.2002.6779
*cite journal | author=Shanks RA, Larocca MC, Berryman M, "et al." |title=AKAP350 at the Golgi apparatus. II. Association of AKAP350 with a novel chloride intracellular channel (CLIC) family member. |journal=J. Biol. Chem. |volume=277 |issue= 43 |pages= 40973–80 |year= 2002 |pmid= 12163479 |doi= 10.1074/jbc.M112277200
*cite journal | author=Takahashi M, Yamagiwa A, Nishimura T, "et al." |title=Centrosomal proteins CG-NAP and kendrin provide microtubule nucleation sites by anchoring gamma-tubulin ring complex. |journal=Mol. Biol. Cell |volume=13 |issue= 9 |pages= 3235–45 |year= 2003 |pmid= 12221128 |doi= 10.1091/mbc.E02-02-0112
*cite journal | author=Sillibourne JE, Milne DM, Takahashi M, "et al." |title=Centrosomal anchoring of the protein kinase CK1delta mediated by attachment to the large, coiled-coil scaffolding protein CG-NAP/AKAP450. |journal=J. Mol. Biol. |volume=322 |issue= 4 |pages= 785–97 |year= 2002 |pmid= 12270714 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Scherer SW, Cheung J, MacDonald JR, "et al." |title=Human chromosome 7: DNA sequence and biology. |journal=Science |volume=300 |issue= 5620 |pages= 767–72 |year= 2003 |pmid= 12690205 |doi= 10.1126/science.1083423
*cite journal | author=Hillier LW, Fulton RS, Fulton LA, "et al." |title=The DNA sequence of human chromosome 7. |journal=Nature |volume=424 |issue= 6945 |pages= 157–64 |year= 2003 |pmid= 12853948 |doi= 10.1038/nature01782
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Tu H, Tang TS, Wang Z, Bezprozvanny I |title=Association of type 1 inositol 1,4,5-trisphosphate receptor with AKAP9 (Yotiao) and protein kinase A. |journal=J. Biol. Chem. |volume=279 |issue= 18 |pages= 19375–82 |year= 2004 |pmid= 14982933 |doi= 10.1074/jbc.M313476200PBB_Controls
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