- ST13
Suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein), also known as ST13, is a human
gene .cite web | title = Entrez Gene: ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6767| accessdate = ]PBB_Summary
section_title =
summary_text = The protein encoded by this gene is an adaptor protein that mediates the association of the heat shock proteins HSP70 and HSP90. This protein has been shown to be involved in the assembly process of glucocorticoid receptor, which requires the assistance of multiple molecular chaperones. The expression of this gene is reported to be downregulated in colorectal carcinoma tissue suggesting that is a candidate tumor suppressor gene.cite web | title = Entrez Gene: ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6767| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Prapapanich V, Chen S, Nair SC, "et al." |title=Molecular cloning of human p48, a transient component of progesterone receptor complexes and an Hsp70-binding protein. |journal=Mol. Endocrinol. |volume=10 |issue= 4 |pages= 420–31 |year= 1996 |pmid= 8721986 |doi=
*cite journal | author=Prapapanich V, Chen S, Toran EJ, "et al." |title=Mutational analysis of the hsp70-interacting protein Hip. |journal=Mol. Cell. Biol. |volume=16 |issue= 11 |pages= 6200–7 |year= 1996 |pmid= 8887650 |doi=
*cite journal | author=Cao J, Cai X, Zheng L, "et al." |title=Characterization of colorectal-cancer-related cDNA clones obtained by subtractive hybridization screening. |journal=J. Cancer Res. Clin. Oncol. |volume=123 |issue= 8 |pages= 447–51 |year= 1997 |pmid= 9292708 |doi=
*cite journal | author=Mo Y, Zheng S, Shen D |title= [Differential expression of HSU17714 gene in colorectal cancer and normal colonic mucosa] |journal=Zhonghua Zhong Liu Za Zhi |volume=18 |issue= 4 |pages= 241–3 |year= 1998 |pmid= 9387309 |doi=
*cite journal | author=Johnson BD, Schumacher RJ, Ross ED, Toft DO |title=Hop modulates Hsp70/Hsp90 interactions in protein folding. |journal=J. Biol. Chem. |volume=273 |issue= 6 |pages= 3679–86 |year= 1998 |pmid= 9452498 |doi=
*cite journal | author=Zheng S, Cai X, Cao J, "et al." |title=Screening and identification of down-regulated genes in colorectal carcinoma by subtractive hybridization: a method to identify putative tumor suppressor genes. |journal=Chin. Med. J. |volume=110 |issue= 7 |pages= 543–7 |year= 1998 |pmid= 9594214 |doi=
*cite journal | author=Chen S, Smith DF |title=Hop as an adaptor in the heat shock protein 70 (Hsp70) and hsp90 chaperone machinery. |journal=J. Biol. Chem. |volume=273 |issue= 52 |pages= 35194–200 |year= 1999 |pmid= 9857057 |doi=
*cite journal | author=Zhang Y, Cai X, Schlegelberger B, Zheng S |title=Assignment1 of human putative tumor suppressor genes ST13 (alias SNC6) and ST14 (alias SNC19) to human chromosome bands 22q13 and 11q24-->q25 by in situ hybridization. |journal=Cytogenet. Cell Genet. |volume=83 |issue= 1-2 |pages= 56–7 |year= 1999 |pmid= 9925927 |doi=
*cite journal | author=Scanlan MJ, Gordan JD, Williamson B, "et al." |title=Antigens recognized by autologous antibody in patients with renal-cell carcinoma. |journal=Int. J. Cancer |volume=83 |issue= 4 |pages= 456–64 |year= 1999 |pmid= 10508479 |doi=
*cite journal | author=Dunham I, Shimizu N, Roe BA, "et al." |title=The DNA sequence of human chromosome 22. |journal=Nature |volume=402 |issue= 6761 |pages= 489–95 |year= 1999 |pmid= 10591208 |doi= 10.1038/990031
*cite journal | author=Morishima Y, Kanelakis KC, Silverstein AM, "et al." |title=The Hsp organizer protein hop enhances the rate of but is not essential for glucocorticoid receptor folding by the multiprotein Hsp90-based chaperone system. |journal=J. Biol. Chem. |volume=275 |issue= 10 |pages= 6894–900 |year= 2000 |pmid= 10702249 |doi=
*cite journal | author=Rajapandi T, Greene LE, Eisenberg E |title=The molecular chaperones Hsp90 and Hsc70 are both necessary and sufficient to activate hormone binding by glucocorticoid receptor. |journal=J. Biol. Chem. |volume=275 |issue= 29 |pages= 22597–604 |year= 2000 |pmid= 10781595 |doi= 10.1074/jbc.M002035200
*cite journal | author=Agarraberes FA, Dice JF |title=A molecular chaperone complex at the lysosomal membrane is required for protein translocation. |journal=J. Cell. Sci. |volume=114 |issue= Pt 13 |pages= 2491–9 |year= 2002 |pmid= 11559757 |doi=
*cite journal | author=Velten M, Gomez-Vrielynck N, Chaffotte A, Ladjimi MM |title=Domain structure of the HSC70 cochaperone, HIP. |journal=J. Biol. Chem. |volume=277 |issue= 1 |pages= 259–66 |year= 2002 |pmid= 11687574 |doi= 10.1074/jbc.M106881200
*cite journal | author=Fan GH, Yang W, Sai J, Richmond A |title=Hsc/Hsp70 interacting protein (hip) associates with CXCR2 and regulates the receptor signaling and trafficking. |journal=J. Biol. Chem. |volume=277 |issue= 8 |pages= 6590–7 |year= 2002 |pmid= 11751889 |doi= 10.1074/jbc.M110588200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Nelson GM, Prapapanich V, Carrigan PE, "et al." |title=The heat shock protein 70 cochaperone hip enhances functional maturation of glucocorticoid receptor. |journal=Mol. Endocrinol. |volume=18 |issue= 7 |pages= 1620–30 |year= 2005 |pmid= 15071092 |doi= 10.1210/me.2004-0054
*cite journal | author=Colland F, Jacq X, Trouplin V, "et al." |title=Functional proteomics mapping of a human signaling pathway. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1324–32 |year= 2004 |pmid= 15231748 |doi= 10.1101/gr.2334104
*cite journal | author=Collins JE, Wright CL, Edwards CA, "et al." |title=A genome annotation-driven approach to cloning the human ORFeome. |journal=Genome Biol. |volume=5 |issue= 10 |pages= R84 |year= 2005 |pmid= 15461802 |doi= 10.1186/gb-2004-5-10-r84
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504PBB_Controls
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