SON DNA binding protein, also known as SON, is a human gene.cite web | title = Entrez Gene: SON SON DNA binding protein| url =| accessdate = ]

section_title =
summary_text = The protein encoded by this gene binds to a specific DNA sequence upstream of the upstream regulatory sequence of the core promoter and second enhancer of human hepatitis B virus (HBV). Through this binding, it represses HBV core promoter activity, transcription of HBV genes, and production of HBV virions. The protein shows sequence similarities with other DNA-binding structural proteins such as gallin, oncoproteins of the MYC family, and the oncoprotein MOS. It may also be involved in protecting cells from apoptosis and in pre-mRNA splicing. Several transcript variants encoding different isoforms have been described for this gene, but the full-length nature of only two of them has been determined.cite web | title = Entrez Gene: SON SON DNA binding protein| url =| accessdate = ]


Further reading

citations =
*cite journal | author=Mattioni T, Hume CR, Konigorski S, "et al." |title=A cDNA clone for a novel nuclear protein with DNA binding activity. |journal=Chromosoma |volume=101 |issue= 10 |pages= 618–24 |year= 1992 |pmid= 1424986 |doi=
*cite journal | author=Bliskovskiĭ VV, Berdichevskiĭ FB, Tkachenko AV, "et al." |title= [Coding part of the son gene small transcript contains four areas of complete tandem repeats] |journal=Mol. Biol. (Mosk.) |volume=26 |issue= 4 |pages= 793–806 |year= 1992 |pmid= 1435773 |doi=
*cite journal | author=Bliskovskiĭ VV, Kirillov AV, Zakhar'ev VM, Chumankov IM |title= [The human son gene: the large and small transcripts contains various 5'-terminal sequences] |journal=Mol. Biol. (Mosk.) |volume=26 |issue= 4 |pages= 807–12 |year= 1992 |pmid= 1435774 |doi=
*cite journal | author=Tassone F, Cheng S, Gardiner K |title=Analysis of chromosome 21 yeast artificial chromosome (YAC) clones. |journal=Am. J. Hum. Genet. |volume=51 |issue= 6 |pages= 1251–64 |year= 1993 |pmid= 1463009 |doi=
*cite journal | author=Chumakov IM, Berdichevskiĭ FB, Sokolova NV, "et al." |title= [Identification of a protein product of a novel human gene SON and the biological effect upon administering a changed form of this gene into mammalian cells] |journal=Mol. Biol. (Mosk.) |volume=25 |issue= 3 |pages= 731–9 |year= 1991 |pmid= 1944255 |doi=
*cite journal | author=Berdichevskiĭ FB, Chumakov IM, Kiselev LL |title= [Decoding of the primary structure of the son3 region in human genome: identification of a new protein with unusual structure and homology with DNA-binding proteins] |journal=Mol. Biol. (Mosk.) |volume=22 |issue= 3 |pages= 794–801 |year= 1988 |pmid= 3054499 |doi=
*cite journal | author=Khan IM, Fisher RA, Johnson KJ, "et al." |title=The SON gene encodes a conserved DNA binding protein mapping to human chromosome 21. |journal=Ann. Hum. Genet. |volume=58 |issue= Pt 1 |pages= 25–34 |year= 1994 |pmid= 8031013 |doi=
*cite journal | author=Cheng S, Lutfalla G, Uze G, "et al." |title=GART, SON, IFNAR, and CRF2-4 genes cluster on human chromosome 21 and mouse chromosome 16. |journal=Mamm. Genome |volume=4 |issue= 6 |pages= 338–42 |year= 1993 |pmid= 8318737 |doi=
*cite journal | author=Kikuno R, Nagase T, Ishikawa K, "et al." |title=Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=6 |issue= 3 |pages= 197–205 |year= 1999 |pmid= 10470851 |doi=
*cite journal | author=Greenhalf W, Lee J, Chaudhuri B |title=A selection system for human apoptosis inhibitors using yeast. |journal=Yeast |volume=15 |issue= 13 |pages= 1307–21 |year= 1999 |pmid= 10509013 |doi= 10.1002/(SICI)1097-0061(19990930)15:13<1307::AID-YEA455>3.0.CO;2-3 |doilabel=10.1002/(SICI)1097-0061(19990930)15:131307::AID-YEA4553.0.CO;2-3
*cite journal | author=Hattori M, Fujiyama A, Taylor TD, "et al." |title=The DNA sequence of human chromosome 21. |journal=Nature |volume=405 |issue= 6784 |pages= 311–9 |year= 2000 |pmid= 10830953 |doi= 10.1038/35012518
*cite journal | author=Wynn SL, Fisher RA, Pagel C, "et al." |title=Organization and conservation of the GART/SON/DONSON locus in mouse and human genomes. |journal=Genomics |volume=68 |issue= 1 |pages= 57–62 |year= 2001 |pmid= 10950926 |doi= 10.1006/geno.2000.6254
*cite journal | author=Sun CT, Lo WY, Wang IH, "et al." |title=Transcription repression of human hepatitis B virus genes by negative regulatory element-binding protein/SON. |journal=J. Biol. Chem. |volume=276 |issue= 26 |pages= 24059–67 |year= 2001 |pmid= 11306577 |doi= 10.1074/jbc.M101330200
*cite journal | author=Reymond A, Friedli M, Henrichsen CN, "et al." |title=From PREDs and open reading frames to cDNA isolation: revisiting the human chromosome 21 transcription map. |journal=Genomics |volume=78 |issue= 1-2 |pages= 46–54 |year= 2002 |pmid= 11707072 |doi= 10.1006/geno.2001.6640
*cite journal | author=Yi J, Kloeker S, Jensen CC, "et al." |title=Members of the Zyxin family of LIM proteins interact with members of the p130Cas family of signal transducers. |journal=J. Biol. Chem. |volume=277 |issue= 11 |pages= 9580–9 |year= 2002 |pmid= 11782456 |doi= 10.1074/jbc.M106922200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Casadei R, Strippoli P, D'Addabbo P, "et al." |title=mRNA 5' region sequence incompleteness: a potential source of systematic errors in translation initiation codon assignment in human mRNAs. |journal=Gene |volume=321 |issue= |pages= 185–93 |year= 2004 |pmid= 14637006 |doi=
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Hillman RT, Green RE, Brenner SE |title=An unappreciated role for RNA surveillance. |journal=Genome Biol. |volume=5 |issue= 2 |pages= R8 |year= 2005 |pmid= 14759258 |doi= 10.1186/gb-2004-5-2-r8
*cite journal | author=Colland F, Jacq X, Trouplin V, "et al." |title=Functional proteomics mapping of a human signaling pathway. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1324–32 |year= 2004 |pmid= 15231748 |doi= 10.1101/gr.2334104

update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes

Wikimedia Foundation. 2010.

Нужно сделать НИР?

Look at other dictionaries:

  • Són — Son cubain Son (cubain) Origines stylistiques changui Origines culturelles Cuba Instrument(s) typique(s) tres, bon …   Wikipédia en Français

  • Son — ist: Isone, Gemeinde im Kanton Tessin (veralteter deutscher Name) Son (Ardennen), Gemeinde im Département Ardennen, Frankreich der Oberlauf des französischen Flusses Son Sonnette ein Ortsteil der Gemeinde Son en Breugel, Nordbrabant Son… …   Deutsch Wikipedia

  • Son — Son, n. [OE. sone, sune, AS. sunu; akin to D. zoon, OS., OFries., & OHG. sunu, G. sohn, Icel. sonr, Sw. son, Dan. s[ o]n, Goth. sunus, Lith. sunus, Russ. suin , Skr. s[=u]nu (from s[=u] to beget, to bear), and Gr. ? son. [root]293. Cf. {Sow}, n.] …   The Collaborative International Dictionary of English

  • Son — es un término que puede referirse a: Música Son: el nombre común de varios géneros musicales de origen afro caribeño mestizo que se cultivan en varios países de la cuenca del mar Caribe, entre los que se cuentan: República Dominicana: Guatemala:… …   Wikipedia Español

  • Son of Oi! — Kompilationsalbum von verschiedenen Interpreten Veröffentlichung 1983 Labels Syndicate Records …   Deutsch Wikipedia

  • SON — steht für: den Landkreis Sonneberg in Thüringen (Kfz Kennzeichen) Sonora, mexikanischer Bundesstaat, siehe Kfz Kennzeichen (Mexiko) eine mit dem japanischen Zen vergleichbare Schule des Buddhismus in Korea, siehe Son (Buddhismus) eine japanische… …   Deutsch Wikipedia

  • Son Mi-na — (* 8. Oktober 1964) ist eine ehemalige südkoreanische Handballspielerin. Sie nahm an zwei Olympischen Spielen teil und sprach 1988 den Olympischen Eid. Son Mi na hatte ihr olympisches Debüt bei den Olympischen Sommerspielen 1984 in Los Angeles.… …   Deutsch Wikipedia

  • Son of Ra — or SAR ( SA for Son and R for Ra or Re) is a title used in occult societies.It was used in Ordre de la Rose Croix Catholique, given only to highest initiates of the Order.SAR was also used by the ancient kings of Assyria.Another explanation for… …   Wikipedia

  • SON-9 — (NATO reporting name Fire Can) is a type of RussianSoviet fire director radar for 57 mm and 100 mm anti aircraft guns.It was widely employed during the Vietnam also* *SON 30 *SON 50External links* [… …   Wikipedia

  • SON-50 — (NATO reporting name Flap Wheel) is a type of RussianSoviet fire director radar for 57 mm anti aircraft guns.It has been widely employed during the Vietnam also*SON 9 *SON 30External links* [ 101/sys/land/row/s 60 …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”