S100 calcium binding protein A8

S100 calcium binding protein A8

S100 calcium binding protein A8, also known as S100A8, is a human gene. [cite web | title = Entrez Gene: S100A8 S100 calcium binding protein A8| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6279| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis.cite web | title = Entrez Gene: S100A8 S100 calcium binding protein A8| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6279| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Schäfer BW, Heizmann CW |title=The S100 family of EF-hand calcium-binding proteins: functions and pathology. |journal=Trends Biochem. Sci. |volume=21 |issue= 4 |pages= 134–40 |year= 1996 |pmid= 8701470 |doi=
*cite journal | author=Kerkhoff C, Klempt M, Sorg C |title=Novel insights into structure and function of MRP8 (S100A8) and MRP14 (S100A9). |journal=Biochim. Biophys. Acta |volume=1448 |issue= 2 |pages= 200–11 |year= 1999 |pmid= 9920411 |doi=
*cite journal | author=Nacken W, Roth J, Sorg C, Kerkhoff C |title=S100A9/S100A8: Myeloid representatives of the S100 protein family as prominent players in innate immunity. |journal=Microsc. Res. Tech. |volume=60 |issue= 6 |pages= 569–80 |year= 2003 |pmid= 12645005 |doi= 10.1002/jemt.10299
*cite journal | author=Roth J, Vogl T, Sorg C, Sunderkötter C |title=Phagocyte-specific S100 proteins: a novel group of proinflammatory molecules. |journal=Trends Immunol. |volume=24 |issue= 4 |pages= 155–8 |year= 2004 |pmid= 12697438 |doi=
*cite journal | author=Rasmussen HH, van Damme J, Puype M, "et al." |title=Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes. |journal=Electrophoresis |volume=13 |issue= 12 |pages= 960–9 |year= 1993 |pmid= 1286667 |doi=
*cite journal | author=Lemarchand P, Vaglio M, Mauël J, Markert M |title=Translocation of a small cytosolic calcium-binding protein (MRP-8) to plasma membrane correlates with human neutrophil activation. |journal=J. Biol. Chem. |volume=267 |issue= 27 |pages= 19379–82 |year= 1992 |pmid= 1326551 |doi=
*cite journal | author=Schäfer T, Sachse GE, Gassen HG |title=The calcium-binding protein MRP-8 is produced by human pulmonary tumor cells. |journal=Biol. Chem. Hoppe-Seyler |volume=372 |issue= 1 |pages= 1–4 |year= 1991 |pmid= 2039599 |doi=
*cite journal | author=Dorin JR, Emslie E, van Heyningen V |title=Related calcium-binding proteins map to the same subregion of chromosome 1q and to an extended region of synteny on mouse chromosome 3. |journal=Genomics |volume=8 |issue= 3 |pages= 420–6 |year= 1991 |pmid= 2149559 |doi=
*cite journal | author=Wilkinson MM, Busuttil A, Hayward C, "et al." |title=Expression pattern of two related cystic fibrosis-associated calcium-binding proteins in normal and abnormal tissues. |journal=J. Cell. Sci. |volume=91 ( Pt 2) |issue= |pages= 221–30 |year= 1989 |pmid= 3267695 |doi=
*cite journal | author=Odink K, Cerletti N, Brüggen J, "et al." |title=Two calcium-binding proteins in infiltrate macrophages of rheumatoid arthritis. |journal=Nature |volume=330 |issue= 6143 |pages= 80–2 |year= 1987 |pmid= 3313057 |doi= 10.1038/330080a0
*cite journal | author=Lagasse E, Clerc RG |title=Cloning and expression of two human genes encoding calcium-binding proteins that are regulated during myeloid differentiation. |journal=Mol. Cell. Biol. |volume=8 |issue= 6 |pages= 2402–10 |year= 1988 |pmid= 3405210 |doi=
*cite journal | author=Dorin JR, Novak M, Hill RE, "et al." |title=A clue to the basic defect in cystic fibrosis from cloning the CF antigen gene. |journal=Nature |volume=326 |issue= 6113 |pages= 614–7 |year= 1987 |pmid= 3561500 |doi= 10.1038/326614a0
*cite journal | author=Schäfer BW, Wicki R, Engelkamp D, "et al." |title=Isolation of a YAC clone covering a cluster of nine S100 genes on human chromosome 1q21: rationale for a new nomenclature of the S100 calcium-binding protein family. |journal=Genomics |volume=25 |issue= 3 |pages= 638–43 |year= 1995 |pmid= 7759097 |doi=
*cite journal | author=Umekawa T, Kurita T |title=Calprotectin-like protein is related to soluble organic matrix in calcium oxalate urinary stone. |journal=Biochem. Mol. Biol. Int. |volume=34 |issue= 2 |pages= 309–13 |year= 1995 |pmid= 7849642 |doi=
*cite journal | author=Engelkamp D, Schäfer BW, Mattei MG, "et al." |title=Six S100 genes are clustered on human chromosome 1q21: identification of two genes coding for the two previously unreported calcium-binding proteins S100D and S100E. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=90 |issue= 14 |pages= 6547–51 |year= 1993 |pmid= 8341667 |doi=
*cite journal | author=Roth J, Burwinkel F, van den Bos C, "et al." |title=MRP8 and MRP14, S-100-like proteins associated with myeloid differentiation, are translocated to plasma membrane and intermediate filaments in a calcium-dependent manner. |journal=Blood |volume=82 |issue= 6 |pages= 1875–83 |year= 1993 |pmid= 8400238 |doi=
*cite journal | author=Miyasaki KT, Bodeau AL, Murthy AR, Lehrer RI |title=In vitro antimicrobial activity of the human neutrophil cytosolic S-100 protein complex, calprotectin, against Capnocytophaga sputigena. |journal=J. Dent. Res. |volume=72 |issue= 2 |pages= 517–23 |year= 1993 |pmid= 8423249 |doi=
*cite journal | author=Marti T, Erttmann KD, Gallin MY |title=Host-parasite interaction in human onchocerciasis: identification and sequence analysis of a novel human calgranulin. |journal=Biochem. Biophys. Res. Commun. |volume=221 |issue= 2 |pages= 454–8 |year= 1996 |pmid= 8619876 |doi= 10.1006/bbrc.1996.0616

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