TRNA nucleotidyltransferase

TRNA nucleotidyltransferase

In enzymology, a tRNA nucleotidyltransferase (EC number|2.7.7.56) is an enzyme that catalyzes the chemical reaction

:tRNAn+1 + phosphate ightleftharpoons tRNAn + a nucleoside diphosphate

Thus, the two substrates of this enzyme are tRNA(n+1) and phosphate, whereas its two products are tRNA(n) and nucleoside diphosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is tRNA:phosphate nucleotidyltransferase. Other names in common use include phosphate-dependent exonuclease, RNase PH, and ribonuclease PH.

tructural studies

As of late 2007, 9 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1OYP, PDB link|1OYR, PDB link|1OYS, PDB link|1R6L, PDB link|1R6M, PDB link|1UDN, PDB link|1UDO, PDB link|1UDQ, and PDB link|1UDS.

References

*
*

External links

::"The CAS registry number for this enzyme class is CAS registry|116412-36-3."

Gene Ontology (GO) codes


Wikimedia Foundation. 2010.

Игры ⚽ Поможем сделать НИР

Look at other dictionaries:

  • TRNA cytidylyltransferase — In enzymology, a tRNA cytidylyltransferase (EC number|2.7.7.21) is an enzyme that catalyzes the chemical reaction:CTP + tRNAn ightleftharpoons diphosphate + tRNAn+1Dubious|date=August 2008Thus, the two substrates of this enzyme are CTP and… …   Wikipedia

  • TRNA adenylyltransferase — In enzymology, a tRNA adenylyltransferase (EC number|2.7.7.25) is an enzyme that catalyzes the chemical reaction:ATP + tRNAn ightleftharpoons diphosphate + tRNAn+1Dubious|date=August 2008Thus, the two substrates of this enzyme are ATP and tRNA(n) …   Wikipedia

  • TRNT1 — tRNA nucleotidyl transferase, CCA adding, 1, also known as TRNT1, is a human gene.cite web | title = Entrez Gene: TRNT1 tRNA nucleotidyl transferase, CCA adding, 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView… …   Wikipedia

  • List of EC numbers (EC 2) — This list contains a list of EC numbers for the second group, EC 2, transferases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 2.1: Transferring One… …   Wikipedia

  • RNA polymerase — RNAP from T. aquaticus pictured during elongation. Portions of the enzyme were made transparent so as to make the path of RNA and DNA more clear. The magnesium ion (yellow) is located at the enzyme active site. RNA polymerase (RNAP or RNApol) is… …   Wikipedia

  • Ribonuclease — Ribonuclease, abbreviated commonly as RNase, is a nuclease that catalyzes the degradation of RNA into smaller components. Ribonucleases can be divided into endoribonucleases and exoribonucleases, and comprise several sub classes within the EC 2.7 …   Wikipedia

  • Creatine kinase — Crystals of creatine kinase Creatine kinase (CK), also known as creatine phosphokinase (CPK) or phospho creatine kinase (and sometimes incorrectly as creatinine kinase), is an enzyme (EC 2.7.3.2) expressed by various tissues and cell types. CK… …   Wikipedia

  • Adenylate kinase — 3D ribbon/surface model of adenylate kinase in complex with bis(adenosine)teraphosphate (ADP ADP) Identifiers Symbol ADK …   Wikipedia

  • RNase PH — protein Name = Ribonuclease PH caption = Structure of the RNase PH hexamer width = 220 HGNCid = Symbol = RNASEPH AltSymbols = EntrezGene = OMIM = RefSeq = UniProt = PDB = ECnumber = 2.7.7.56 Chromosome = Arm = Band = LocusSupplementaryData =… …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”