RNA uridylyltransferase

In enzymology, a RNA uridylyltransferase (EC number|2.7.7.52) is an enzyme that catalyzes the chemical reaction

:UTP + RNAn $ightleftharpoons$ diphosphate + RNAn⁺1

Thus, the two substrates of this enzyme are UTP and RNAn, whereas its two products are diphosphate and RNAn+1.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is UTP:RNA uridylyltransferase. Other names in common use include terminal uridylyltransferase, and TUT.

tructural studies

As of late 2007, 8 structures have been solved for this class of enzymes, with PDB accession codes PDB link|2E5G, PDB link|2IKF, PDB link|2NOM, PDB link|2Q0C, PDB link|2Q0D, PDB link|2Q0E, PDB link|2Q0F, and PDB link|2Q0G.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|78519-53-6."

Gene Ontology (GO) codes