Opacity family porins

Opacity family porins
Opacity family porin protein
PDB 1p4t EBI.jpg
Structure of Neisserial surface protein A (NspA).[1]
Identifiers
Symbol Opacity
Pfam PF02462
InterPro IPR003394
SCOP 1p4t
OPM family 26
OPM protein 1p4t

Opacity family porins are a family of porins from pathogenic Neisseria. These bacteria possess a repertoire of phase-variable opacity proteins that mediate various pathogen/host cell interactions.[2] These proteins are related to OmpA-like transmembrane domain family.

References

  1. ^ Vandeputte-Rutten L, Bos MP, Tommassen J, Gros P (July 2003). "Crystal structure of Neisserial surface protein A (NspA), a conserved outer membrane protein with vaccine potential". J. Biol. Chem. 278 (27): 24825–30. doi:10.1074/jbc.M302803200. PMID 12716881. 
  2. ^ Meyer TF, Dehio C, Gray-owen SD (1998). "The role of neisserial Opa proteins in interactions with host cells". Trends Microbiol. 6 (12): 489–495. doi:10.1016/S0966-842X(98)01365-1. PMID 10036728.