- Leucine transaminase
In
enzymology , a leucine transaminase (EC number|2.6.1.6) is anenzyme that catalyzes thechemical reaction :L-leucine + 2-oxoglutarate 4-methyl-2-oxopentanoate + L-glutamate
Thus, the two substrates of this enzyme are
L-leucine and2-oxoglutarate , whereas its two products are4-methyl-2-oxopentanoate andL-glutamate .This enzyme belongs to the family of
transferase s, specifically thetransaminases , which transfer nitrogenous groups. The systematic name of this enzyme class is L-leucine:2-oxoglutarate aminotransferase. Other names in common use include L-leucine aminotransferase, leucine 2-oxoglutarate transaminase, leucine aminotransferase, and leucine-alpha-ketoglutarate transaminase. This enzyme participates in 3 metabolic pathways:valine, leucine and isoleucine degradation ,valine, leucine and isoleucine biosynthesis , andpantothenate and coa biosynthesis . It employs one cofactor,pyridoxal phosphate .References
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*External links
::"The
CAS registry number for this enzyme class is CAS registry|9030-37-9."Gene Ontology (GO) codes
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