Glutamine-pyruvate transaminase
- Glutamine-pyruvate transaminase
In enzymology, a glutamine-pyruvate transaminase (EC number|2.6.1.15) is an enzyme that catalyzes the chemical reaction
:L-glutamine + pyruvate 2-oxoglutaramate + L-alanine
Thus, the two substrates of this enzyme are L-glutamine and pyruvate, whereas its two products are 2-oxoglutaramate and L-alanine.
This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is L-glutamine:pyruvate aminotransferase. Other names in common use include glutaminase II, L-glutamine transaminase L, and glutamine-oxo-acid transaminase. This enzyme participates in glutamate metabolism. It employs one cofactor, pyridoxal phosphate.
tructural studies
As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1V2D, PDB link|1V2E, and PDB link|1V2F.
References
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External links
::"The CAS registry number for this enzyme class is CAS registry|9030-44-8."
Gene Ontology (GO) codes
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