Chitin deacetylase

Chitin deacetylase
chitin deacetylase
Identifiers
EC number 3.5.1.41
CAS number 56379-60-3
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a chitin deacetylase (EC 3.5.1.41) is an enzyme that catalyzes the chemical reaction

chitin + H2O \rightleftharpoons chitosan + acetate

Thus, the two substrates of this enzyme are chitin and H2O, whereas its two products are chitosan and acetate.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is chitin amidohydrolase. This enzyme participates in aminosugars metabolism.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 2IW0.

References

  • Araki Y, Ito E (1974). "A pathway of chitosan formation in Mucor rouxii: enzymatic deacetylation of chitin". Biochem. Biophys. Res. Commun. 56 (3): 669–75. doi:10.1016/0006-291X(74)90657-3. PMID 4826874. 
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