Arylalkyl acylamidase

Arylalkyl acylamidase
arylalkyl acylamidase
Identifiers
EC number 3.5.1.76
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, an arylalkyl acylamidase (EC 3.5.1.76) is an enzyme that catalyzes the chemical reaction

N-acetylarylalkylamine + H2O \rightleftharpoons arylalkylamine + acetate

Thus, the two substrates of this enzyme are N-acetylarylalkylamine and H2O, whereas its two products are arylalkylamine and acetate.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-acetylarylalkylamine amidohydrolase. This enzyme is also called aralkyl acylamidase.

References

  • Shimizu S, Ogawa J, Chung MC, Yamada H (1992). "Purification and characterization of a novel enzyme, arylalkyl acylamidase, from Pseudomonas putida Sc2". Eur. J. Biochem. 209 (1): 375–82. doi:10.1111/j.1432-1033.1992.tb17299.x. PMID 1396711.