Palmitoyl(protein) hydrolase

Palmitoyl(protein) hydrolase

In enzymology, a palmitoyl [protein] hydrolase (EC number|3.1.2.22) is an enzyme that catalyzes the chemical reaction

:palmitoyl [protein] + H2O ightleftharpoons palmitate + protein

Thus, the two substrates of this enzyme are [palmitoyl [protein] and H2O, whereas its two products are palmitate and protein.

This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name of this enzyme class is palmitoyl [protein] hydrolase. Other names in common use include palmitoyl-protein thioesterase, and palmitoyl-(protein) hydrolase. This enzyme participates in fatty acid elongation in mitochondria.

tructural studies

As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1EH5, PDB link|1EI9, PDB link|1EXW, and PDB link|1PJA.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|150605-49-5."

Gene Ontology (GO) codes


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