Palmitoyl(protein) hydrolase

Palmitoyl(protein) hydrolase

In enzymology, a palmitoyl [protein] hydrolase (EC number|3.1.2.22) is an enzyme that catalyzes the chemical reaction

:palmitoyl [protein] + H2O ightleftharpoons palmitate + protein

Thus, the two substrates of this enzyme are [palmitoyl [protein] and H2O, whereas its two products are palmitate and protein.

This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name of this enzyme class is palmitoyl [protein] hydrolase. Other names in common use include palmitoyl-protein thioesterase, and palmitoyl-(protein) hydrolase. This enzyme participates in fatty acid elongation in mitochondria.

tructural studies

As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1EH5, PDB link|1EI9, PDB link|1EXW, and PDB link|1PJA.

References

*
*
*

External links

::"The CAS registry number for this enzyme class is CAS registry|150605-49-5."

Gene Ontology (GO) codes


Wikimedia Foundation. 2010.

Игры ⚽ Поможем написать реферат

Look at other dictionaries:

  • Protein tyrosine phosphatase — Protein tyrosine phosphatases (PTPs) are a group of enzymes that remove phosphate groups from phosphorylated tyrosine residues on proteins. Protein tyrosine (pTyr) phosphorylation is a common post translational modification that can create novel… …   Wikipedia

  • Hydrolase — Cristal de lysozyme Les hydrolases constituent une classe d enzymes qui catalysent les réactions d hydrolyse de molécules suivant la réaction générale : R R + H2O ⇌ R OH + R H On y trouve par exemple les estérases, qui hydrolysent les …   Wikipédia en Français

  • List of EC numbers (EC 3) — This list contains a list of EC numbers for the third group, EC 3, hydrolases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 3.1: Acting on Ester BondsEC… …   Wikipedia

  • Arylsulfatase A — PDB rendering based on 1auk …   Wikipedia

  • N-acyl phosphatidylethanolamine-specific phospholipase D — N acyl phosphatidylethanolamine phospholipase D Identifiers Symbol NAPEPLD Entrez 222236 HUGO …   Wikipedia

  • Metabolism — Cell metabolism redirects here. For the journal, see Cell Metabolism. Structure of adenosine triphosphate, a central intermediate in energy metabolism Metabolism (from Greek: μεταβολή metabolē , change or Greek: μεταβολισμός metabolismos,… …   Wikipedia

  • Deoxyribonuclease I — Identifiers Symbols DNASE1; DKFZp686H0155; DNL1; DRNI; FLJ38093; FLJ44902 External IDs …   Wikipedia

  • PDE4B — Phosphodiesterase 4B, cAMP specific PDB rendering based on 1f0j …   Wikipedia

  • PDE4A — Phosphodiesterase 4A, cAMP specific PDB rendering based on 1loi …   Wikipedia

  • OCRL — Oculocerebrorenal syndrome of Lowe PDB rendering based on 2qv2 …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”