ADP-dependent short-chain-acyl-CoA hydrolase

ADP-dependent short-chain-acyl-CoA hydrolase

In enzymology, an ADP-dependent short-chain-acyl-CoA hydrolase (EC number|3.1.2.18) is an enzyme that catalyzes the chemical reaction

:acyl-CoA + H2O ightleftharpoons CoA + a carboxylate

Thus, the two substrates of this enzyme are acyl-CoA and H2O, whereas its two products are CoA and carboxylate.

This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name of this enzyme class is ADP-dependent-short-chain-acyl-CoA hydrolase. Other names in common use include short-chain acyl coenzyme A hydrolase, propionyl coenzyme A hydrolase, propionyl-CoA hydrolase, propionyl-CoA thioesterase, short-chain acyl-CoA hydrolase, and short-chain acyl-CoA thioesterase. It employs one cofactor, ADP. At least one compound, NADH is known to inhibit this enzyme.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|117698-16-5."

Gene Ontology (GO) codes


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