Acetate-CoA ligase (ADP-forming)
- Acetate-CoA ligase (ADP-forming)
In enzymology, an acetate-CoA ligase (ADP-forming) (EC number|6.2.1.13) is an enzyme that catalyzes the chemical reaction
:ATP + acetate + CoA ADP + phosphate + acetyl-CoA
The 3 substrates of this enzyme are ATP, acetate, and CoA, whereas its 3 products are ADP, phosphate, and acetyl-CoA.
This enzyme belongs to the family of ligases, specifically those forming carbon-sulfur bonds as acid-thiol ligases. The systematic name of this enzyme class is acetate:CoA ligase (ADP-forming). Other names in common use include acetyl-CoA synthetase (ADP-forming), acetyl coenzyme A synthetase (adenosine diphosphate-forming), and acetate thiokinase. This enzyme participates in pyruvate metabolism and propanoate metabolism.
References
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External links
::"The CAS registry number for this enzyme class is CAS registry|62009-85-2."
Gene Ontology (GO) codes
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Look at other dictionaries:
acetate — A salt or ester of acetic acid. active a. SYN: acetyl CoA. a. kinase [EC 2.7.2.1] a phosphotransferase forming acetyl phosphate and ADP from ATP and a.. An important enzyme in the formation of “high energy” phosphate in certain microorganisms.… … Medical dictionary
acetyl-CoA — Condensation product of coenzyme A and acetic acid, symbolized as CoAS∼COCH3; intermediate in transfer of two carbon fragment, notably in its entrance into the tricarboxylic acid cycle and in fatty acid synthesis. SYN: acetyl coenzyme A … Medical dictionary
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Thiokinase — can refer to: * Acetate CoA ligase (ADP forming) * Butyrate CoA ligase * Citrate CoA ligase * Malate CoA ligase * Succinate CoA ligase (ADP forming) * Succinate CoA ligase (GDP forming) … Wikipedia
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Citric acid cycle — Overview of the citric acid cycle The citric acid cycle also known as the tricarboxylic acid cycle (TCA cycle), the Krebs cycle, or the Szent Györgyi Krebs cycle[1] … Wikipedia
List of EC numbers (EC 3) — This list contains a list of EC numbers for the third group, EC 3, hydrolases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 3.1: Acting on Ester BondsEC… … Wikipedia
pyruvate — A salt or ester of pyruvic acid. active p. an intermediate formed in the oxidative decarboxylation of p.. Cf.:p. dehydrogenase (lipoamide). SYN: α lactyl thiamin pyrophosphate. p. carboxylase ligase … Medical dictionary
metabolism — /meuh tab euh liz euhm/, n. 1. Biol., Physiol. the sum of the physical and chemical processes in an organism by which its material substance is produced, maintained, and destroyed, and by which energy is made available. Cf. anabolism, catabolism … Universalium
Citrate synthase — Identifiers Symbol CS Entrez 1431 HUGO … Wikipedia
