Steroid sulfotransferase

In enzymology, a steroid sulfotransferase (EC number|2.8.2.15) is an enzyme that catalyzes the chemical reaction

:3'-phosphoadenylyl sulfate + a phenolic steroid $ightleftharpoons$ adenosine 3',5'-bisphosphate + steroid O-sulfate

Thus, the two substrates of this enzyme are 3'-phosphoadenylyl sulfate and phenolic steroid, whereas its two products are adenosine 3',5'-bisphosphate and steroid O-sulfate.

This enzyme belongs to the family of transferases, specifically the sulfotransferases, which transfer sulfur-containing groups. The systematic name of this enzyme class is 3'-phosphoadenylyl-sulfate:phenolic-steroid sulfotransferase. This enzyme is also called steroid alcohol sulfotransferase. This enzyme participates in androgen and estrogen metabolism.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|9032-76-2."

Gene Ontology (GO) codes