CSNK2B

Casein kinase 2, beta polypeptide, also known as CSNK2B, is a human gene.

PBB_Summary
section_title =
summary_text = This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus. [cite web | title = Entrez Gene: CSNK2B casein kinase 2, beta polypeptide| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1460| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Schubert U, Schneider T, Henklein P, "et al." |title=Human-immunodeficiency-virus-type-1-encoded Vpu protein is phosphorylated by casein kinase II. |journal=Eur. J. Biochem. |volume=204 |issue= 2 |pages= 875–83 |year= 1992 |pmid= 1541298 |doi=
*cite journal | author=Teitz T, Eli D, Penner M, "et al." |title=Expression of the cDNA for the beta subunit of human casein kinase II confers partial UV resistance on xeroderma pigmentosum cells. |journal=Mutat. Res. |volume=236 |issue= 1 |pages= 85–97 |year= 1990 |pmid= 1694965 |doi=
*cite journal | author=Voss H, Wirkner U, Jakobi R, "et al." |title=Structure of the gene encoding human casein kinase II subunit beta. |journal=J. Biol. Chem. |volume=266 |issue= 21 |pages= 13706–11 |year= 1991 |pmid= 1856204 |doi=
*cite journal | author=Litchfield DW, Lozeman FJ, Cicirelli MF, "et al." |title=Phosphorylation of the beta subunit of casein kinase II in human A431 cells. Identification of the autophosphorylation site and a site phosphorylated by p34cdc2. |journal=J. Biol. Chem. |volume=266 |issue= 30 |pages= 20380–9 |year= 1991 |pmid= 1939094 |doi=
*cite journal | author=Yang-Feng TL, Teitz T, Cheung MC, "et al." |title=Assignment of the human casein kinase II beta-subunit gene to 6p12----p21. |journal=Genomics |volume=8 |issue= 4 |pages= 741–2 |year= 1991 |pmid= 2276748 |doi=
*cite journal | author=Ackerman P, Glover CV, Osheroff N |title=Stimulation of casein kinase II by epidermal growth factor: relationship between the physiological activity of the kinase and the phosphorylation state of its beta subunit. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=87 |issue= 2 |pages= 821–5 |year= 1990 |pmid= 2300566 |doi=
*cite journal | author=Heller-Harrison RA, Meisner H, Czech MP |title=Cloning and characterization of a cDNA encoding the beta subunit of human casein kinase II. |journal=Biochemistry |volume=28 |issue= 23 |pages= 9053–8 |year= 1990 |pmid= 2513884 |doi=
*cite journal | author=Jakobi R, Voss H, Pyerin W |title=Human phosvitin/casein kinase type II. Molecular cloning and sequencing of full-length cDNA encoding subunit beta. |journal=Eur. J. Biochem. |volume=183 |issue= 1 |pages= 227–33 |year= 1989 |pmid= 2666134 |doi=
*cite journal | author=Vincent MJ, Abdul Jabbar M |title=The human immunodeficiency virus type 1 Vpu protein: a potential regulator of proteolysis and protein transport in the mammalian secretory pathway. |journal=Virology |volume=213 |issue= 2 |pages= 639–49 |year= 1996 |pmid= 7491787 |doi=
*cite journal | author=Litchfield DW, Bosc DG, Slominski E |title=The protein kinase from mitotic human cells that phosphorylates Ser-209 on the casein kinase II beta-subunit is p34cdc2. |journal=Biochim. Biophys. Acta |volume=1269 |issue= 1 |pages= 69–78 |year= 1995 |pmid= 7578274 |doi=
*cite journal | author=Jin YJ, Burakoff SJ |title=The 25-kDa FK506-binding protein is localized in the nucleus and associates with casein kinase II and nucleolin. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=90 |issue= 16 |pages= 7769–73 |year= 1993 |pmid= 7689229 |doi=
*cite journal | author=Gietz RD, Graham KC, Litchfield DW |title=Interactions between the subunits of casein kinase II. |journal=J. Biol. Chem. |volume=270 |issue= 22 |pages= 13017–21 |year= 1995 |pmid= 7768894 |doi=
*cite journal | author=Szebeni A, Herrera JE, Olson MO |title=Interaction of nucleolar protein B23 with peptides related to nuclear localization signals. |journal=Biochemistry |volume=34 |issue= 25 |pages= 8037–42 |year= 1995 |pmid= 7794916 |doi=
*cite journal | author=Arnold SF, Obourn JD, Jaffe H, Notides AC |title=Serine 167 is the major estradiol-induced phosphorylation site on the human estrogen receptor. |journal=Mol. Endocrinol. |volume=8 |issue= 9 |pages= 1208–14 |year= 1995 |pmid= 7838153 |doi=
*cite journal | author=Pyerin W |title=Human casein kinase II: structures, genes, expression and requirement in cell growth stimulation. |journal=Adv. Enzyme Regul. |volume=34 |issue= |pages= 225–46 |year= 1994 |pmid= 7942276 |doi=
*cite journal | author=el Benna J, Faust LP, Babior BM |title=The phosphorylation of the respiratory burst oxidase component p47phox during neutrophil activation. Phosphorylation of sites recognized by protein kinase C and by proline-directed kinases. |journal=J. Biol. Chem. |volume=269 |issue= 38 |pages= 23431–6 |year= 1994 |pmid= 8089108 |doi=
*cite journal | author=Schubert U, Henklein P, Boldyreff B, "et al." |title=The human immunodeficiency virus type 1 encoded Vpu protein is phosphorylated by casein kinase-2 (CK-2) at positions Ser52 and Ser56 within a predicted alpha-helix-turn-alpha-helix-motif. |journal=J. Mol. Biol. |volume=236 |issue= 1 |pages= 16–25 |year= 1994 |pmid= 8107101 |doi= 10.1006/jmbi.1994.1114
*cite journal | author=Schubert U, Strebel K |title=Differential activities of the human immunodeficiency virus type 1-encoded Vpu protein are regulated by phosphorylation and occur in different cellular compartments. |journal=J. Virol. |volume=68 |issue= 4 |pages= 2260–71 |year= 1994 |pmid= 8139011 |doi=
*cite journal | author=Tanasijevic MJ, Myers MG, Thoma RS, "et al." |title=Phosphorylation of the insulin receptor substrate IRS-1 by casein kinase II. |journal=J. Biol. Chem. |volume=268 |issue= 24 |pages= 18157–66 |year= 1993 |pmid= 8349691 |doi=
*cite journal | author=Friborg J, Ladha A, Göttlinger H, "et al." |title=Functional analysis of the phosphorylation sites on the human immunodeficiency virus type 1 Vpu protein. |journal=J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. |volume=8 |issue= 1 |pages= 10–22 |year= 1996 |pmid= 8548340 |doi=

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