SKIV2L

Superkiller viralicidic activity 2-like (S. cerevisiae), also known as SKIV2L, is a human gene.cite web | title = Entrez Gene: SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6499| accessdate = ]

PBB_Summary
section_title =
summary_text = DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a human homologue of yeast SKI2 and may be involved in antiviral activity by blocking translation of poly(A) deficient mRNAs. This gene is located in the class III region of the major histocompatibility complex.cite web | title = Entrez Gene: SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6499| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Yang Z, Qu X, Yu CY |title=Features of the two gene pairs RD-SKI2W and DOM3Z-RP1 located between complement component genes factor B and C4 at the MHC class III region. |journal=Front. Biosci. |volume=6 |issue= |pages= D927–35 |year= 2001 |pmid= 11487501 |doi=
*cite journal | author=Dangel AW, Shen L, Mendoza AR, "et al." |title=Human helicase gene SKI2W in the HLA class III region exhibits striking structural similarities to the yeast antiviral gene SKI2 and to the human gene KIAA0052: emergence of a new gene family. |journal=Nucleic Acids Res. |volume=23 |issue= 12 |pages= 2120–6 |year= 1995 |pmid= 7610041 |doi=
*cite journal | author=Lee SG, Lee I, Park SH, "et al." |title=Identification and characterization of a human cDNA homologous to yeast SKI2. |journal=Genomics |volume=25 |issue= 3 |pages= 660–6 |year= 1995 |pmid= 7759100 |doi=
*cite journal | author=Shen L, Wu LC, Sanlioglu S, "et al." |title=Structure and genetics of the partially duplicated gene RP located immediately upstream of the complement C4A and the C4B genes in the HLA class III region. Molecular cloning, exon-intron structure, composite retroposon, and breakpoint of gene duplication. |journal=J. Biol. Chem. |volume=269 |issue= 11 |pages= 8466–76 |year= 1994 |pmid= 8132574 |doi=
*cite journal | author=Albertella MR, Jones H, Thomson W, "et al." |title=Localization of eight additional genes in the human major histocompatibility complex, including the gene encoding the casein kinase II beta subunit (CSNK2B). |journal=Genomics |volume=36 |issue= 2 |pages= 240–51 |year= 1997 |pmid= 8812450 |doi= 10.1006/geno.1996.0459
*cite journal | author=Lee SG, Song K |title=Genomic organization of the human DDX13 gene located between RD and RP1 in the class III MHC complex. |journal=Mol. Cells |volume=7 |issue= 3 |pages= 414–8 |year= 1997 |pmid= 9264031 |doi=
*cite journal | author=Qu X, Yang Z, Zhang S, "et al." |title=The human DEVH-box protein Ski2w from the HLA is localized in nucleoli and ribosomes. |journal=Nucleic Acids Res. |volume=26 |issue= 17 |pages= 4068–77 |year= 1998 |pmid= 9705521 |doi=
*cite journal | author=Yang Z, Shen L, Dangel AW, "et al." |title=Four ubiquitously expressed genes, RD (D6S45)-SKI2W (SKIV2L)-DOM3Z-RP1 (D6S60E), are present between complement component genes factor B and C4 in the class III region of the HLA. |journal=Genomics |volume=53 |issue= 3 |pages= 338–47 |year= 1998 |pmid= 9799600 |doi= 10.1006/geno.1998.5499
*cite journal | author=Lee SG, Song K |title=Identification and characterization of a bidirectional promoter from the intergenic region between the human DDX13 and RD genes. |journal=Mol. Cells |volume=10 |issue= 1 |pages= 47–53 |year= 2000 |pmid= 10774746 |doi=
*cite journal | author=Chen CY, Gherzi R, Ong SE, "et al." |title=AU binding proteins recruit the exosome to degrade ARE-containing mRNAs. |journal=Cell |volume=107 |issue= 4 |pages= 451–64 |year= 2002 |pmid= 11719186 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Lehner B, Sanderson CM |title=A protein interaction framework for human mRNA degradation. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1315–23 |year= 2004 |pmid= 15231747 |doi= 10.1101/gr.2122004
*cite journal | author=Beausoleil SA, Jedrychowski M, Schwartz D, "et al." |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Beausoleil SA, Villén J, Gerber SA, "et al." |title=A probability-based approach for high-throughput protein phosphorylation analysis and site localization. |journal=Nat. Biotechnol. |volume=24 |issue= 10 |pages= 1285–92 |year= 2006 |pmid= 16964243 |doi= 10.1038/nbt1240
*cite journal | author=Olsen JV, Blagoev B, Gnad F, "et al." |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026
*cite journal | author=Yang CT, Hindes AE, Hultman KA, Johnson SL |title=Mutations in gfpt1 and skiv2l2 cause distinct stage-specific defects in larval melanocyte regeneration in zebrafish. |journal=PLoS Genet. |volume=3 |issue= 6 |pages= e88 |year= 2007 |pmid= 17542649 |doi= 10.1371/journal.pgen.0030088

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