RDBP

RD RNA binding protein, also known as RDBP, is a human gene.cite web | title = Entrez Gene: RDBP RD RNA binding protein| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7936| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is part of a complex termed negative elongation factor (NELF) which represses RNA polymerase II transcript elongation. This protein bears similarity to nuclear RNA-binding proteins; however, it has not been demonstrated that this protein binds RNA. The protein contains a tract of alternating basic and acidic residues, largely arginine (R) and aspartic acid (D). The gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6.cite web | title = Entrez Gene: RDBP RD RNA binding protein| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7936| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Yu CY |title=Molecular genetics of the human MHC complement gene cluster. |journal=Exp. Clin. Immunogenet. |volume=15 |issue= 4 |pages= 213–30 |year= 1999 |pmid= 10072631 |doi=
*cite journal | author=Stevens M, De Clercq E, Balzarini J |title=The regulation of HIV-1 transcription: molecular targets for chemotherapeutic intervention. |journal=Med Res Rev |volume=26 |issue= 5 |pages= 595–625 |year= 2007 |pmid= 16838299 |doi= 10.1002/med.20081
*cite journal | author=Surowy CS, Hoganson G, Gosink J, "et al." |title=The human RD protein is closely related to nuclear RNA-binding proteins and has been highly conserved. |journal=Gene |volume=90 |issue= 2 |pages= 299–302 |year= 1990 |pmid= 2119325 |doi=
*cite journal | author=Speiser PW, White PC |title=Structure of the human RD gene: a highly conserved gene in the class III region of the major histocompatibility complex. |journal=DNA |volume=8 |issue= 10 |pages= 745–51 |year= 1990 |pmid= 2612324 |doi=
*cite journal | author=Lévi-Strauss M, Carroll MC, Steinmetz M, Meo T |title=A previously undetected MHC gene with an unusual periodic structure. |journal=Science |volume=240 |issue= 4849 |pages= 201–4 |year= 1988 |pmid= 3353717 |doi=
*cite journal | author=Cheng J, Macon KJ, Volanakis JE |title=cDNA cloning and characterization of the protein encoded by RD, a gene located in the class III region of the human major histocompatibility complex. |journal=Biochem. J. |volume=294 ( Pt 2) |issue= |pages= 589–93 |year= 1993 |pmid= 8373374 |doi=
*cite journal | author=Lee SG, Song K |title=Genomic organization of the human DDX13 gene located between RD and RP1 in the class III MHC complex. |journal=Mol. Cells |volume=7 |issue= 3 |pages= 414–8 |year= 1997 |pmid= 9264031 |doi=
*cite journal | author=Büssow K, Cahill D, Nietfeld W, "et al." |title=A method for global protein expression and antibody screening on high-density filters of an arrayed cDNA library. |journal=Nucleic Acids Res. |volume=26 |issue= 21 |pages= 5007–8 |year= 1998 |pmid= 9776767 |doi=
*cite journal | author=Yang Z, Shen L, Dangel AW, "et al." |title=Four ubiquitously expressed genes, RD (D6S45)-SKI2W (SKIV2L)-DOM3Z-RP1 (D6S60E), are present between complement component genes factor B and C4 in the class III region of the HLA. |journal=Genomics |volume=53 |issue= 3 |pages= 338–47 |year= 1998 |pmid= 9799600 |doi= 10.1006/geno.1998.5499
*cite journal | author=Yamaguchi Y, Takagi T, Wada T, "et al." |title=NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation. |journal=Cell |volume=97 |issue= 1 |pages= 41–51 |year= 1999 |pmid= 10199401 |doi=
*cite journal | author=Ping YH, Rana TM |title=DSIF and NELF interact with RNA polymerase II elongation complex and HIV-1 Tat stimulates P-TEFb-mediated phosphorylation of RNA polymerase II and DSIF during transcription elongation. |journal=J. Biol. Chem. |volume=276 |issue= 16 |pages= 12951–8 |year= 2001 |pmid= 11112772 |doi= 10.1074/jbc.M006130200
*cite journal | author=Yamaguchi Y, Inukai N, Narita T, "et al." |title=Evidence that negative elongation factor represses transcription elongation through binding to a DRB sensitivity-inducing factor/RNA polymerase II complex and RNA. |journal=Mol. Cell. Biol. |volume=22 |issue= 9 |pages= 2918–27 |year= 2002 |pmid= 11940650 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Narita T, Yamaguchi Y, Yano K, "et al." |title=Human transcription elongation factor NELF: identification of novel subunits and reconstitution of the functionally active complex. |journal=Mol. Cell. Biol. |volume=23 |issue= 6 |pages= 1863–73 |year= 2003 |pmid= 12612062 |doi=
*cite journal | author=Mungall AJ, Palmer SA, Sims SK, "et al." |title=The DNA sequence and analysis of human chromosome 6. |journal=Nature |volume=425 |issue= 6960 |pages= 805–11 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055
*cite journal | author=Xie T, Rowen L, Aguado B, "et al." |title=Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse. |journal=Genome Res. |volume=13 |issue= 12 |pages= 2621–36 |year= 2004 |pmid= 14656967 |doi= 10.1101/gr.1736803
*cite journal | author=Lehner B, Semple JI, Brown SE, "et al." |title=Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region. |journal=Genomics |volume=83 |issue= 1 |pages= 153–67 |year= 2004 |pmid= 14667819 |doi=
*cite journal | author=Beausoleil SA, Jedrychowski M, Schwartz D, "et al." |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101
*cite journal | author=Aiyar SE, Sun JL, Blair AL, "et al." |title=Attenuation of estrogen receptor alpha-mediated transcription through estrogen-stimulated recruitment of a negative elongation factor. |journal=Genes Dev. |volume=18 |issue= 17 |pages= 2134–46 |year= 2004 |pmid= 15342491 |doi= 10.1101/gad.1214104

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = no
update_citations = yes