APOM

APOM

Apolipoprotein M, also known as APOM, is a human gene.cite web | title = Entrez Gene: APOM apolipoprotein M| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55937| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is an apolipoprotein and member of the lipocalin protein family. It is found associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. The encoded protein is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. Two transcript variants encoding two different isoforms have been found for this gene, but only one of them has been fully characterized.cite web | title = Entrez Gene: APOM apolipoprotein M| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55937| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Albertella MR, Jones H, Thomson W, "et al." |title=Localization of eight additional genes in the human major histocompatibility complex, including the gene encoding the casein kinase II beta subunit (CSNK2B). |journal=Genomics |volume=36 |issue= 2 |pages= 240–51 |year= 1997 |pmid= 8812450 |doi= 10.1006/geno.1996.0459
*cite journal | author=Xu N, Dahlbäck B |title=A novel human apolipoprotein (apoM). |journal=J. Biol. Chem. |volume=274 |issue= 44 |pages= 31286–90 |year= 1999 |pmid= 10531326 |doi=
*cite journal | author=Duan J, Dahlbäck B, Villoutreix BO |title=Proposed lipocalin fold for apolipoprotein M based on bioinformatics and site-directed mutagenesis. |journal=FEBS Lett. |volume=499 |issue= 1-2 |pages= 127–32 |year= 2001 |pmid= 11418126 |doi=
*cite journal | author=Xu N, Zhang XY, Dong X, "et al." |title=Effects of platelet-activating factor, tumor necrosis factor, and interleukin-1alpha on the expression of apolipoprotein M in HepG2 cells. |journal=Biochem. Biophys. Res. Commun. |volume=292 |issue= 4 |pages= 944–50 |year= 2002 |pmid= 11944906 |doi= 10.1006/bbrc.2002.6755
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Zhang XY, Dong X, Zheng L, "et al." |title=Specific tissue expression and cellular localization of human apolipoprotein M as determined by in situ hybridization. |journal=Acta Histochem. |volume=105 |issue= 1 |pages= 67–72 |year= 2003 |pmid= 12666989 |doi=
*cite journal | author=Mungall AJ, Palmer SA, Sims SK, "et al." |title=The DNA sequence and analysis of human chromosome 6. |journal=Nature |volume=425 |issue= 6960 |pages= 805–11 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055
*cite journal | author=Richter S, Shih DQ, Pearson ER, "et al." |title=Regulation of apolipoprotein M gene expression by MODY3 gene hepatocyte nuclear factor-1alpha: haploinsufficiency is associated with reduced serum apolipoprotein M levels. |journal=Diabetes |volume=52 |issue= 12 |pages= 2989–95 |year= 2004 |pmid= 14633861 |doi=
*cite journal | author=Xie T, Rowen L, Aguado B, "et al." |title=Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse. |journal=Genome Res. |volume=13 |issue= 12 |pages= 2621–36 |year= 2004 |pmid= 14656967 |doi= 10.1101/gr.1736803
*cite journal | author=Zhang XY, Jiao GQ, Hurtig M, "et al." |title=Expression pattern of apolipoprotein M during mouse and human embryogenesis. |journal=Acta Histochem. |volume=106 |issue= 2 |pages= 123–8 |year= 2005 |pmid= 15147633 |doi= 10.1016/j.acthis.2003.11.004
*cite journal | author=Kabbara A, Payet N, Cottel D, "et al." |title=Exclusion of CYP46 and APOM as candidate genes for Alzheimer's disease in a French population. |journal=Neurosci. Lett. |volume=363 |issue= 2 |pages= 139–43 |year= 2004 |pmid= 15172102 |doi= 10.1016/j.neulet.2004.03.066
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Xu N, Nilsson-Ehle P, Ahrén B |title=Correlation of apolipoprotein M with leptin and cholesterol in normal and obese subjects. |journal=J. Nutr. Biochem. |volume=15 |issue= 10 |pages= 579–82 |year= 2005 |pmid= 15542348 |doi= 10.1016/j.jnutbio.2004.03.001
*cite journal | author=Luo G, Hurtig M, Zhang X, "et al." |title=Leptin inhibits apolipoprotein M transcription and secretion in human hepatoma cell line, HepG2 cells. |journal=Biochim. Biophys. Acta |volume=1734 |issue= 2 |pages= 198–202 |year= 2005 |pmid= 15904876 |doi= 10.1016/j.bbalip.2005.02.005
*cite journal | author=Liu T, Qian WJ, Gritsenko MA, "et al." |title=Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. |journal=J. Proteome Res. |volume=4 |issue= 6 |pages= 2070–80 |year= 2006 |pmid= 16335952 |doi= 10.1021/pr0502065
*cite journal | author=Niu N, Zhu X, Liu Y, "et al." |title=Single nucleotide polymorphisms in the proximal promoter region of apolipoprotein M gene (apoM) confer the susceptibility to development of type 2 diabetes in Han Chinese. |journal=Diabetes Metab. Res. Rev. |volume=23 |issue= 1 |pages= 21–5 |year= 2007 |pmid= 16572495 |doi= 10.1002/dmrr.641
*cite journal | author=Christoffersen C, Nielsen LB, Axler O, "et al." |title=Isolation and characterization of human apolipoprotein M-containing lipoproteins. |journal=J. Lipid Res. |volume=47 |issue= 8 |pages= 1833–43 |year= 2006 |pmid= 16682745 |doi= 10.1194/jlr.M600055-JLR200
*cite journal | author=Karlsson H, Lindqvist H, Tagesson C, Lindahl M |title=Characterization of apolipoprotein M isoforms in low-density lipoprotein. |journal=J. Proteome Res. |volume=5 |issue= 10 |pages= 2685–90 |year= 2006 |pmid= 17022639 |doi= 10.1021/pr060180x
*cite journal | author=Xu X, Ye Q, Xu N, "et al." |title=Effects of ischemia-reperfusion injury on apolipoprotein M expression in the liver. |journal=Transplant. Proc. |volume=38 |issue= 9 |pages= 2769–73 |year= 2007 |pmid= 17112825 |doi= 10.1016/j.transproceed.2006.08.133
*cite journal | author=Ahnström J, Faber K, Axler O, Dahlbäck B |title=Hydrophobic ligand binding properties of the human lipocalin apolipoprotein M. |journal=J. Lipid Res. |volume=48 |issue= 8 |pages= 1754–62 |year= 2007 |pmid= 17525477 |doi= 10.1194/jlr.M700103-JLR200

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