- AP1G1
Adaptor-related protein complex 1, gamma 1 subunit, also known as AP1G1, is a human
gene .PBB_Summary
section_title =
summary_text = Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. Two transcript variants encoding different isoforms have been found for this gene.cite web | title = Entrez Gene: AP1G1 adaptor-related protein complex 1, gamma 1 subunit| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=164| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Peyrard M, Parveneh S, Lagercrantz S, "et al." |title=Cloning, expression pattern, and chromosomal assignment to 16q23 of the human gamma-adaptin gene (ADTG). |journal=Genomics |volume=50 |issue= 2 |pages= 275–80 |year= 1998 |pmid= 9653655 |doi= 10.1006/geno.1998.5289
*cite journal | author=Takatsu H, Sakurai M, Shin HW, "et al." |title=Identification and characterization of novel clathrin adaptor-related proteins. |journal=J. Biol. Chem. |volume=273 |issue= 38 |pages= 24693–700 |year= 1998 |pmid= 9733768 |doi=
*cite journal | author=Berlioz-Torrent C, Shacklett BL, Erdtmann L, "et al." |title=Interactions of the cytoplasmic domains of human and simian retroviral transmembrane proteins with components of the clathrin adaptor complexes modulate intracellular and cell surface expression of envelope glycoproteins. |journal=J. Virol. |volume=73 |issue= 2 |pages= 1350–61 |year= 1999 |pmid= 9882340 |doi=
*cite journal | author=Page LJ, Sowerby PJ, Lui WW, Robinson MS |title=Gamma-synergin: an EH domain-containing protein that interacts with gamma-adaptin. |journal=J. Cell Biol. |volume=146 |issue= 5 |pages= 993–1004 |year= 1999 |pmid= 10477754 |doi=
*cite journal | author=Fölsch H, Ohno H, Bonifacino JS, Mellman I |title=A novel clathrin adaptor complex mediates basolateral targeting in polarized epithelial cells. |journal=Cell |volume=99 |issue= 2 |pages= 189–98 |year= 1999 |pmid= 10535737 |doi=
*cite journal | author=Hirst J, Lui WW, Bright NA, "et al." |title=A family of proteins with gamma-adaptin and VHS domains that facilitate trafficking between the trans-Golgi network and the vacuole/lysosome. |journal=J. Cell Biol. |volume=149 |issue= 1 |pages= 67–80 |year= 2000 |pmid= 10747088 |doi=
*cite journal | author=Takatsu H, Yoshino K, Nakayama K |title=Adaptor gamma ear homology domain conserved in gamma-adaptin and GGA proteins that interact with gamma-synergin. |journal=Biochem. Biophys. Res. Commun. |volume=271 |issue= 3 |pages= 719–25 |year= 2000 |pmid= 10814529 |doi= 10.1006/bbrc.2000.2700
*cite journal | author=Nakagawa T, Setou M, Seog D, "et al." |title=A novel motor, KIF13A, transports mannose-6-phosphate receptor to plasma membrane through direct interaction with AP-1 complex. |journal=Cell |volume=103 |issue= 4 |pages= 569–81 |year= 2001 |pmid= 11106728 |doi=
*cite journal | author=Wyss S, Berlioz-Torrent C, Boge M, "et al." |title=The highly conserved C-terminal dileucine motif in the cytosolic domain of the human immunodeficiency virus type 1 envelope glycoprotein is critical for its association with the AP-1 clathrin adaptor [correction of adapter] . |journal=J. Virol. |volume=75 |issue= 6 |pages= 2982–92 |year= 2001 |pmid= 11222723 |doi= 10.1128/JVI.75.6.2982-2992.2001
*cite journal | author=Crump CM, Xiang Y, Thomas L, "et al." |title=PACS-1 binding to adaptors is required for acidic cluster motif-mediated protein traffic. |journal=EMBO J. |volume=20 |issue= 9 |pages= 2191–201 |year= 2001 |pmid= 11331585 |doi= 10.1093/emboj/20.9.2191
*cite journal | author=Takatsu H, Futatsumori M, Yoshino K, "et al." |title=Similar subunit interactions contribute to assembly of clathrin adaptor complexes and COPI complex: analysis using yeast three-hybrid system. |journal=Biochem. Biophys. Res. Commun. |volume=284 |issue= 4 |pages= 1083–9 |year= 2001 |pmid= 11409905 |doi= 10.1006/bbrc.2001.5081
*cite journal | author=Orzech E, Livshits L, Leyt J, "et al." |title=Interactions between adaptor protein-1 of the clathrin coat and microtubules via type 1a microtubule-associated proteins. |journal=J. Biol. Chem. |volume=276 |issue= 33 |pages= 31340–8 |year= 2001 |pmid= 11418592 |doi= 10.1074/jbc.M101054200
*cite journal | author=Doray B, Kornfeld S |title=Gamma subunit of the AP-1 adaptor complex binds clathrin: implications for cooperative binding in coated vesicle assembly. |journal=Mol. Biol. Cell |volume=12 |issue= 7 |pages= 1925–35 |year= 2001 |pmid= 11451993 |doi=
*cite journal | author=Shiba Y, Takatsu H, Shin HW, Nakayama K |title=Gamma-adaptin interacts directly with Rabaptin-5 through its ear domain. |journal=J. Biochem. |volume=131 |issue= 3 |pages= 327–36 |year= 2002 |pmid= 11872161 |doi=
*cite journal | author=Austin C, Boehm M, Tooze SA |title=Site-specific cross-linking reveals a differential direct interaction of class 1, 2, and 3 ADP-ribosylation factors with adaptor protein complexes 1 and 3. |journal=Biochemistry |volume=41 |issue= 14 |pages= 4669–77 |year= 2002 |pmid= 11926829 |doi=
*cite journal | author=Eiraku M, Hirata Y, Takeshima H, "et al." |title=Delta/notch-like epidermal growth factor (EGF)-related receptor, a novel EGF-like repeat-containing protein targeted to dendrites of developing and adult central nervous system neurons. |journal=J. Biol. Chem. |volume=277 |issue= 28 |pages= 25400–7 |year= 2002 |pmid= 11950833 |doi= 10.1074/jbc.M110793200
*cite journal | author=Nogi T, Shiba Y, Kawasaki M, "et al." |title=Structural basis for the accessory protein recruitment by the gamma-adaptin ear domain. |journal=Nat. Struct. Biol. |volume=9 |issue= 7 |pages= 527–31 |year= 2002 |pmid= 12042876 |doi= 10.1038/nsb808
*cite journal | author=Kalthoff C, Groos S, Kohl R, "et al." |title=Clint: a novel clathrin-binding ENTH-domain protein at the Golgi. |journal=Mol. Biol. Cell |volume=13 |issue= 11 |pages= 4060–73 |year= 2003 |pmid= 12429846 |doi= 10.1091/mbc.E02-03-0171PBB_Controls
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