ABI1

Abl-interactor 1, also known as ABI1, is a human gene.

PBB_Summary
section_title =
summary_text = The protein encoded by this gene has been found to form a complex with EPS8 and SOS1, and is thought to be involved in the transduction of signals from Ras to Rac. In addition, the encoded protein may play a role in the regulation of EGF-induced Erk pathway activation as well as cytoskeletal reorganization and EGFR signaling. Several transcript variants encoding multiple isoforms have been found for this gene.cite web | title = Entrez Gene: ABI1 abl-interactor 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10006| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Ichigotani Y, Fujii K, Hamaguchi M, Matsuda S |title=In search of a function for the E3B1/Abi2/Argbp1/NESH family (Review). |journal=Int. J. Mol. Med. |volume=9 |issue= 6 |pages= 591–5 |year= 2002 |pmid= 12011975 |doi=
*cite journal | author=Di Fiore PP, Scita G |title=Eps8 in the midst of GTPases. |journal=Int. J. Biochem. Cell Biol. |volume=34 |issue= 10 |pages= 1178–83 |year= 2002 |pmid= 12127568 |doi=
*cite journal | author=Cardwell C |title=Student or worker? International Meeting of Student Nurses (European Group). |journal=Nursing mirror and midwives journal |volume=143 |issue= 19 |pages= 38 |year= 1977 |pmid= 1049958 |doi=
*cite journal | author=Biesova Z, Piccoli C, Wong WT |title=Isolation and characterization of e3B1, an eps8 binding protein that regulates cell growth. |journal=Oncogene |volume=14 |issue= 2 |pages= 233–41 |year= 1997 |pmid= 9010225 |doi= 10.1038/sj.onc.1200822
*cite journal | author=Ziemnicka-Kotula D, Xu J, Gu H, "et al." |title=Identification of a candidate human spectrin Src homology 3 domain-binding protein suggests a general mechanism of association of tyrosine kinases with the spectrin-based membrane skeleton. |journal=J. Biol. Chem. |volume=273 |issue= 22 |pages= 13681–92 |year= 1998 |pmid= 9593709 |doi=
*cite journal | author=Taki T, Shibuya N, Taniwaki M, "et al." |title=ABI-1, a human homolog to mouse Abl-interactor 1, fuses the MLL gene in acute myeloid leukemia with t(10;11)(p11.2;q23). |journal=Blood |volume=92 |issue= 4 |pages= 1125–30 |year= 1998 |pmid= 9694699 |doi=
*cite journal | author=Scita G, Nordstrom J, Carbone R, "et al." |title=EPS8 and E3B1 transduce signals from Ras to Rac. |journal=Nature |volume=401 |issue= 6750 |pages= 290–3 |year= 1999 |pmid= 10499589 |doi= 10.1038/45822
*cite journal | author=Courtney KD, Grove M, Vandongen H, "et al." |title=Localization and phosphorylation of Abl-interactor proteins, Abi-1 and Abi-2, in the developing nervous system. |journal=Mol. Cell. Neurosci. |volume=16 |issue= 3 |pages= 244–57 |year= 2000 |pmid= 10995551 |doi= 10.1006/mcne.2000.0865
*cite journal | author=Fan PD, Goff SP |title=Abl interactor 1 binds to sos and inhibits epidermal growth factor- and v-Abl-induced activation of extracellular signal-regulated kinases. |journal=Mol. Cell. Biol. |volume=20 |issue= 20 |pages= 7591–601 |year= 2000 |pmid= 11003655 |doi=
*cite journal | author=Xu J, Ziemnicka D, Merz GS, Kotula L |title=Human spectrin Src homology 3 domain binding protein 1 regulates macropinocytosis in NIH 3T3 cells. |journal=J. Cell. Sci. |volume=113 Pt 21 |issue= |pages= 3805–14 |year= 2001 |pmid= 11034908 |doi=
*cite journal | author=Lanzetti L, Rybin V, Malabarba MG, "et al." |title=The Eps8 protein coordinates EGF receptor signalling through Rac and trafficking through Rab5. |journal=Nature |volume=408 |issue= 6810 |pages= 374–7 |year= 2000 |pmid= 11099046 |doi= 10.1038/35042605
*cite journal | author=Yamamoto A, Suzuki T, Sakaki Y |title=Isolation of hNap1BP which interacts with human Nap1 (NCKAP1) whose expression is down-regulated in Alzheimer's disease. |journal=Gene |volume=271 |issue= 2 |pages= 159–69 |year= 2001 |pmid= 11418237 |doi=
*cite journal | author=Cowan CA, Henkemeyer M |title=The SH2/SH3 adaptor Grb4 transduces B-ephrin reverse signals. |journal=Nature |volume=413 |issue= 6852 |pages= 174–9 |year= 2001 |pmid= 11557983 |doi= 10.1038/35093123
*cite journal | author=Ichigotani Y, Yokozaki S, Fukuda Y, "et al." |title=Forced expression of NESH suppresses motility and metastatic dissemination of malignant cells. |journal=Cancer Res. |volume=62 |issue= 8 |pages= 2215–9 |year= 2002 |pmid= 11956071 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Salomon AR, Ficarro SB, Brill LM, "et al." |title=Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 2 |pages= 443–8 |year= 2003 |pmid= 12522270 |doi= 10.1073/pnas.2436191100
*cite journal | author=Morerio C, Rosanda C, Rapella A, "et al." |title=Is t(10;11)(p11.2;q23) involving MLL and ABI-1 genes associated with congenital acute monocytic leukemia? |journal=Cancer Genet. Cytogenet. |volume=139 |issue= 1 |pages= 57–9 |year= 2003 |pmid= 12547160 |doi=
*cite journal | author=Gevaert K, Goethals M, Martens L, "et al." |title=Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. |journal=Nat. Biotechnol. |volume=21 |issue= 5 |pages= 566–9 |year= 2004 |pmid= 12665801 |doi= 10.1038/nbt810

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