- AP1M1
Adaptor-related protein complex 1, mu 1 subunit, also known as AP1M1, is a human
gene .PBB_Summary
section_title =
summary_text = The protein encoded by this gene is the medium chain of the trans-Golgi network clathrin-associated protein complex AP-1. The other components of this complex are beta-prime-adaptin, gamma-adaptin, and the small chain AP1S1. This complex is located at the Golgi vesicle and links clathrin to receptors in coated vesicles. These vesicles are involved in endocytosis and Golgi processing.cite web | title = Entrez Gene: AP1M1 adaptor-related protein complex 1, mu 1 subunit| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8907| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Geyer M, Fackler OT, Peterlin BM |title=Structure--function relationships in HIV-1 Nef. |journal=EMBO Rep. |volume=2 |issue= 7 |pages= 580–5 |year= 2001 |pmid= 11463741 |doi= 10.1093/embo-reports/kve141
*cite journal | author=Bénichou S, Benmerah A |title= [The HIV nef and the Kaposi-sarcoma-associated virus K3/K5 proteins: "parasites"of the endocytosis pathway] |journal=Med Sci (Paris) |volume=19 |issue= 1 |pages= 100–6 |year= 2003 |pmid= 12836198 |doi=
*cite journal | author=Ohno H, Stewart J, Fournier MC, "et al." |title=Interaction of tyrosine-based sorting signals with clathrin-associated proteins. |journal=Science |volume=269 |issue= 5232 |pages= 1872–5 |year= 1995 |pmid= 7569928 |doi=
*cite journal | author=Page LJ, Robinson MS |title=Targeting signals and subunit interactions in coated vesicle adaptor complexes. |journal=J. Cell Biol. |volume=131 |issue= 3 |pages= 619–30 |year= 1995 |pmid= 7593184 |doi=
*cite journal | author=Seaman MN, Sowerby PJ, Robinson MS |title=Cytosolic and membrane-associated proteins involved in the recruitment of AP-1 adaptors onto the trans-Golgi network. |journal=J. Biol. Chem. |volume=271 |issue= 41 |pages= 25446–51 |year= 1996 |pmid= 8810314 |doi=
*cite journal | author=Mangasarian A, Foti M, Aiken C, "et al." |title=The HIV-1 Nef protein acts as a connector with sorting pathways in the Golgi and at the plasma membrane. |journal=Immunity |volume=6 |issue= 1 |pages= 67–77 |year= 1997 |pmid= 9052838 |doi=
*cite journal | author=Foti M, Mangasarian A, Piguet V, "et al." |title=Nef-mediated clathrin-coated pit formation. |journal=J. Cell Biol. |volume=139 |issue= 1 |pages= 37–47 |year= 1998 |pmid= 9314527 |doi=
*cite journal | author=Ohno H, Aguilar RC, Fournier MC, "et al." |title=Interaction of endocytic signals from the HIV-1 envelope glycoprotein complex with members of the adaptor medium chain family. |journal=Virology |volume=238 |issue= 2 |pages= 305–15 |year= 1998 |pmid= 9400603 |doi= 10.1006/viro.1997.8839
*cite journal | author=Piguet V, Chen YL, Mangasarian A, "et al." |title=Mechanism of Nef-induced CD4 endocytosis: Nef connects CD4 with the mu chain of adaptor complexes. |journal=EMBO J. |volume=17 |issue= 9 |pages= 2472–81 |year= 1998 |pmid= 9564030 |doi= 10.1093/emboj/17.9.2472
*cite journal | author=Le Gall S, Erdtmann L, Benichou S, "et al." |title=Nef interacts with the mu subunit of clathrin adaptor complexes and reveals a cryptic sorting signal in MHC I molecules. |journal=Immunity |volume=8 |issue= 4 |pages= 483–95 |year= 1998 |pmid= 9586638 |doi=
*cite journal | author=Peyrard M, Parveneh S, Lagercrantz S, "et al." |title=Cloning, expression pattern, and chromosomal assignment to 16q23 of the human gamma-adaptin gene (ADTG). |journal=Genomics |volume=50 |issue= 2 |pages= 275–80 |year= 1998 |pmid= 9653655 |doi= 10.1006/geno.1998.5289
*cite journal | author=Craig HM, Pandori MW, Guatelli JC |title=Interaction of HIV-1 Nef with the cellular dileucine-based sorting pathway is required for CD4 down-regulation and optimal viral infectivity. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 19 |pages= 11229–34 |year= 1998 |pmid= 9736718 |doi=
*cite journal | author=Bresnahan PA, Yonemoto W, Ferrell S, "et al." |title=A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor. |journal=Curr. Biol. |volume=8 |issue= 22 |pages= 1235–8 |year= 1999 |pmid= 9811606 |doi=
*cite journal | author=Greenberg M, DeTulleo L, Rapoport I, "et al." |title=A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4. |journal=Curr. Biol. |volume=8 |issue= 22 |pages= 1239–42 |year= 1999 |pmid= 9811611 |doi=
*cite journal | author=Owen DJ, Evans PR |title=A structural explanation for the recognition of tyrosine-based endocytotic signals. |journal=Science |volume=282 |issue= 5392 |pages= 1327–32 |year= 1998 |pmid= 9812899 |doi=
*cite journal | author=Berlioz-Torrent C, Shacklett BL, Erdtmann L, "et al." |title=Interactions of the cytoplasmic domains of human and simian retroviral transmembrane proteins with components of the clathrin adaptor complexes modulate intracellular and cell surface expression of envelope glycoproteins. |journal=J. Virol. |volume=73 |issue= 2 |pages= 1350–61 |year= 1999 |pmid= 9882340 |doi=
*cite journal | author=Fölsch H, Ohno H, Bonifacino JS, Mellman I |title=A novel clathrin adaptor complex mediates basolateral targeting in polarized epithelial cells. |journal=Cell |volume=99 |issue= 2 |pages= 189–98 |year= 1999 |pmid= 10535737 |doi=
*cite journal | author=Orzech E, Cohen S, Weiss A, Aroeti B |title=Interactions between the exocytic and endocytic pathways in polarized Madin-Darby canine kidney cells. |journal=J. Biol. Chem. |volume=275 |issue= 20 |pages= 15207–19 |year= 2000 |pmid= 10809756 |doi=
*cite journal | author=Umeda A, Meyerholz A, Ungewickell E |title=Identification of the universal cofactor (auxilin 2) in clathrin coat dissociation. |journal=Eur. J. Cell Biol. |volume=79 |issue= 5 |pages= 336–42 |year= 2000 |pmid= 10887964 |doi=
*cite journal | author=Nakagawa T, Setou M, Seog D, "et al." |title=A novel motor, KIF13A, transports mannose-6-phosphate receptor to plasma membrane through direct interaction with AP-1 complex. |journal=Cell |volume=103 |issue= 4 |pages= 569–81 |year= 2001 |pmid= 11106728 |doi=PBB_Controls
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