AP1M1

AP1M1

Adaptor-related protein complex 1, mu 1 subunit, also known as AP1M1, is a human gene.

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is the medium chain of the trans-Golgi network clathrin-associated protein complex AP-1. The other components of this complex are beta-prime-adaptin, gamma-adaptin, and the small chain AP1S1. This complex is located at the Golgi vesicle and links clathrin to receptors in coated vesicles. These vesicles are involved in endocytosis and Golgi processing.cite web | title = Entrez Gene: AP1M1 adaptor-related protein complex 1, mu 1 subunit| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8907| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Geyer M, Fackler OT, Peterlin BM |title=Structure--function relationships in HIV-1 Nef. |journal=EMBO Rep. |volume=2 |issue= 7 |pages= 580–5 |year= 2001 |pmid= 11463741 |doi= 10.1093/embo-reports/kve141
*cite journal | author=Bénichou S, Benmerah A |title= [The HIV nef and the Kaposi-sarcoma-associated virus K3/K5 proteins: "parasites"of the endocytosis pathway] |journal=Med Sci (Paris) |volume=19 |issue= 1 |pages= 100–6 |year= 2003 |pmid= 12836198 |doi=
*cite journal | author=Ohno H, Stewart J, Fournier MC, "et al." |title=Interaction of tyrosine-based sorting signals with clathrin-associated proteins. |journal=Science |volume=269 |issue= 5232 |pages= 1872–5 |year= 1995 |pmid= 7569928 |doi=
*cite journal | author=Page LJ, Robinson MS |title=Targeting signals and subunit interactions in coated vesicle adaptor complexes. |journal=J. Cell Biol. |volume=131 |issue= 3 |pages= 619–30 |year= 1995 |pmid= 7593184 |doi=
*cite journal | author=Seaman MN, Sowerby PJ, Robinson MS |title=Cytosolic and membrane-associated proteins involved in the recruitment of AP-1 adaptors onto the trans-Golgi network. |journal=J. Biol. Chem. |volume=271 |issue= 41 |pages= 25446–51 |year= 1996 |pmid= 8810314 |doi=
*cite journal | author=Mangasarian A, Foti M, Aiken C, "et al." |title=The HIV-1 Nef protein acts as a connector with sorting pathways in the Golgi and at the plasma membrane. |journal=Immunity |volume=6 |issue= 1 |pages= 67–77 |year= 1997 |pmid= 9052838 |doi=
*cite journal | author=Foti M, Mangasarian A, Piguet V, "et al." |title=Nef-mediated clathrin-coated pit formation. |journal=J. Cell Biol. |volume=139 |issue= 1 |pages= 37–47 |year= 1998 |pmid= 9314527 |doi=
*cite journal | author=Ohno H, Aguilar RC, Fournier MC, "et al." |title=Interaction of endocytic signals from the HIV-1 envelope glycoprotein complex with members of the adaptor medium chain family. |journal=Virology |volume=238 |issue= 2 |pages= 305–15 |year= 1998 |pmid= 9400603 |doi= 10.1006/viro.1997.8839
*cite journal | author=Piguet V, Chen YL, Mangasarian A, "et al." |title=Mechanism of Nef-induced CD4 endocytosis: Nef connects CD4 with the mu chain of adaptor complexes. |journal=EMBO J. |volume=17 |issue= 9 |pages= 2472–81 |year= 1998 |pmid= 9564030 |doi= 10.1093/emboj/17.9.2472
*cite journal | author=Le Gall S, Erdtmann L, Benichou S, "et al." |title=Nef interacts with the mu subunit of clathrin adaptor complexes and reveals a cryptic sorting signal in MHC I molecules. |journal=Immunity |volume=8 |issue= 4 |pages= 483–95 |year= 1998 |pmid= 9586638 |doi=
*cite journal | author=Peyrard M, Parveneh S, Lagercrantz S, "et al." |title=Cloning, expression pattern, and chromosomal assignment to 16q23 of the human gamma-adaptin gene (ADTG). |journal=Genomics |volume=50 |issue= 2 |pages= 275–80 |year= 1998 |pmid= 9653655 |doi= 10.1006/geno.1998.5289
*cite journal | author=Craig HM, Pandori MW, Guatelli JC |title=Interaction of HIV-1 Nef with the cellular dileucine-based sorting pathway is required for CD4 down-regulation and optimal viral infectivity. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 19 |pages= 11229–34 |year= 1998 |pmid= 9736718 |doi=
*cite journal | author=Bresnahan PA, Yonemoto W, Ferrell S, "et al." |title=A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor. |journal=Curr. Biol. |volume=8 |issue= 22 |pages= 1235–8 |year= 1999 |pmid= 9811606 |doi=
*cite journal | author=Greenberg M, DeTulleo L, Rapoport I, "et al." |title=A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4. |journal=Curr. Biol. |volume=8 |issue= 22 |pages= 1239–42 |year= 1999 |pmid= 9811611 |doi=
*cite journal | author=Owen DJ, Evans PR |title=A structural explanation for the recognition of tyrosine-based endocytotic signals. |journal=Science |volume=282 |issue= 5392 |pages= 1327–32 |year= 1998 |pmid= 9812899 |doi=
*cite journal | author=Berlioz-Torrent C, Shacklett BL, Erdtmann L, "et al." |title=Interactions of the cytoplasmic domains of human and simian retroviral transmembrane proteins with components of the clathrin adaptor complexes modulate intracellular and cell surface expression of envelope glycoproteins. |journal=J. Virol. |volume=73 |issue= 2 |pages= 1350–61 |year= 1999 |pmid= 9882340 |doi=
*cite journal | author=Fölsch H, Ohno H, Bonifacino JS, Mellman I |title=A novel clathrin adaptor complex mediates basolateral targeting in polarized epithelial cells. |journal=Cell |volume=99 |issue= 2 |pages= 189–98 |year= 1999 |pmid= 10535737 |doi=
*cite journal | author=Orzech E, Cohen S, Weiss A, Aroeti B |title=Interactions between the exocytic and endocytic pathways in polarized Madin-Darby canine kidney cells. |journal=J. Biol. Chem. |volume=275 |issue= 20 |pages= 15207–19 |year= 2000 |pmid= 10809756 |doi=
*cite journal | author=Umeda A, Meyerholz A, Ungewickell E |title=Identification of the universal cofactor (auxilin 2) in clathrin coat dissociation. |journal=Eur. J. Cell Biol. |volume=79 |issue= 5 |pages= 336–42 |year= 2000 |pmid= 10887964 |doi=
*cite journal | author=Nakagawa T, Setou M, Seog D, "et al." |title=A novel motor, KIF13A, transports mannose-6-phosphate receptor to plasma membrane through direct interaction with AP-1 complex. |journal=Cell |volume=103 |issue= 4 |pages= 569–81 |year= 2001 |pmid= 11106728 |doi=

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes


Wikimedia Foundation. 2010.

Игры ⚽ Нужен реферат?

Look at other dictionaries:

  • Caveolae — In biology, caveolae (Latin for little caves, singular: caveola), which are a special type of lipid raft, are small (50–100 nanometer) invaginations of the plasma membrane in many vertebrate cell types, especially in endothelial cells and… …   Wikipedia

  • Small GTPase — Small GTPases are a family of hydrolase enzymes that can bind and hydrolyze guanosine triphosphate (GTP). They are a form of G proteins found in the cytosol which are homologous to the alpha subunit of heterotrimeric G proteins, but unlike the… …   Wikipedia

  • Clathrin — clathrin, light polypeptide (Lca) Identifiers Symbol CLTA Entrez 1211 HUGO …   Wikipedia

  • COPII — For the 1996 United Nations Climate Change Conference in Geneva, Switzerland‎, see COP 2 (climate conference). Sec23 homolog A Ribbon diagram of the crystallographic structure of the COPII heterodimer of Sec23 and Sec24. Alpha helices are in red… …   Wikipedia

  • COPI — C terminal domain Identifiers Symbol COPI C Pfam PF06957 InterPro …   Wikipedia

  • Synaptic vesicle — Neuron A (transmitting) to neuron B (receiving) 1. Mitochondria 2. synaptic vesicle with neurotransmitters 3. Autoreceptor 4. Synapse with neurotransmitter released (serotonin) 5. Postsynaptic receptors activated by neurotransmitter (induction of …   Wikipedia

  • Receptor-mediated endocytosis — Mechanism of clathrin dependent endocytosis. Receptor mediated endocytosis (RME), also called clathrin dependent endocytosis, is a process by which cells internalize molecules (endocytosis) by the inward budding of plasma membrane vesicles… …   Wikipedia

  • SNARE (protein) — Molecular machinery driving vesicle fusion in neuromediator release. The core SNARE complex is formed by four α helices contributed by synaptobrevin, syntaxin and SNAP 25, synaptotagmin serves as a calcium sensor and regulates intimately the… …   Wikipedia

  • Dynamin — N structure of the nucleotide free myosin ii motor domain from dictyostelium discoideum fused to the gtpase domain of dynamin 1 from rattus norvegicus Identifiers Symbol Dynamin N …   Wikipedia

  • Archain — 1 Identifiers Symbol ARCN1 Alt. symbols COPD Entrez 372 H …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”