CUL4A

Cullin 4A, also known as CUL4A, is a human gene. [cite web | title = Entrez Gene: CUL4A Cullin 4A| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8451| accessdate = ]

PBB_Summary
section_title =
summary_text =

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Kipreos ET, Lander LE, Wing JP, "et al." |title=cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family. |journal=Cell |volume=85 |issue= 6 |pages= 829–39 |year= 1996 |pmid= 8681378 |doi=
*cite journal | author=Osaka F, Kawasaki H, Aida N, "et al." |title=A new NEDD8-ligating system for cullin-4A. |journal=Genes Dev. |volume=12 |issue= 15 |pages= 2263–8 |year= 1998 |pmid= 9694792 |doi=
*cite journal | author=Chen LC, Manjeshwar S, Lu Y, "et al." |title=The human homologue for the Caenorhabditis elegans cul-4 gene is amplified and overexpressed in primary breast cancers. |journal=Cancer Res. |volume=58 |issue= 16 |pages= 3677–83 |year= 1998 |pmid= 9721878 |doi=
*cite journal | author=Ohta T, Michel JJ, Schottelius AJ, Xiong Y |title=ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity. |journal=Mol. Cell |volume=3 |issue= 4 |pages= 535–41 |year= 1999 |pmid= 10230407 |doi=
*cite journal | author=Hori T, Osaka F, Chiba T, "et al." |title=Covalent modification of all members of human cullin family proteins by NEDD8. |journal=Oncogene |volume=18 |issue= 48 |pages= 6829–34 |year= 2000 |pmid= 10597293 |doi= 10.1038/sj.onc.1203093
*cite journal | author=Lyapina S, Cope G, Shevchenko A, "et al." |title=Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome. |journal=Science |volume=292 |issue= 5520 |pages= 1382–5 |year= 2001 |pmid= 11337588 |doi= 10.1126/science.1059780
*cite journal | author=Chen X, Zhang Y, Douglas L, Zhou P |title=UV-damaged DNA-binding proteins are targets of CUL-4A-mediated ubiquitination and degradation. |journal=J. Biol. Chem. |volume=276 |issue= 51 |pages= 48175–82 |year= 2002 |pmid= 11673459 |doi= 10.1074/jbc.M106808200
*cite journal | author=Yasui K, Arii S, Zhao C, "et al." |title=TFDP1, CUL4A, and CDC16 identified as targets for amplification at 13q34 in hepatocellular carcinomas. |journal=Hepatology |volume=35 |issue= 6 |pages= 1476–84 |year= 2002 |pmid= 12029633 |doi= 10.1053/jhep.2002.33683
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Liu J, Furukawa M, Matsumoto T, Xiong Y |title=NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases. |journal=Mol. Cell |volume=10 |issue= 6 |pages= 1511–8 |year= 2003 |pmid= 12504025 |doi=
*cite journal | author=Min KW, Hwang JW, Lee JS, "et al." |title=TIP120A associates with cullins and modulates ubiquitin ligase activity. |journal=J. Biol. Chem. |volume=278 |issue= 18 |pages= 15905–10 |year= 2003 |pmid= 12609982 |doi= 10.1074/jbc.M213070200
*cite journal | author=Groisman R, Polanowska J, Kuraoka I, "et al." |title=The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage. |journal=Cell |volume=113 |issue= 3 |pages= 357–67 |year= 2003 |pmid= 12732143 |doi=
*cite journal | author=Higa LA, Mihaylov IS, Banks DP, "et al." |title=Radiation-mediated proteolysis of CDT1 by CUL4-ROC1 and CSN complexes constitutes a new checkpoint. |journal=Nat. Cell Biol. |volume=5 |issue= 11 |pages= 1008–15 |year= 2004 |pmid= 14578910 |doi= 10.1038/ncb1061
*cite journal | author=Wertz IE, O'Rourke KM, Zhang Z, "et al." |title=Human De-etiolated-1 regulates c-Jun by assembling a CUL4A ubiquitin ligase. |journal=Science |volume=303 |issue= 5662 |pages= 1371–4 |year= 2004 |pmid= 14739464 |doi= 10.1126/science.1093549
*cite journal | author=Obuse C, Yang H, Nozaki N, "et al." |title=Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of the CEN-complex, while BMI-1 is transiently co-localized with the centromeric region in interphase. |journal=Genes Cells |volume=9 |issue= 2 |pages= 105–20 |year= 2004 |pmid= 15009096 |doi=
*cite journal | author=Dunham A, Matthews LH, Burton J, "et al." |title=The DNA sequence and analysis of human chromosome 13. |journal=Nature |volume=428 |issue= 6982 |pages= 522–8 |year= 2004 |pmid= 15057823 |doi= 10.1038/nature02379
*cite journal | author=Hu J, McCall CM, Ohta T, Xiong Y |title=Targeted ubiquitination of CDT1 by the DDB1-CUL4A-ROC1 ligase in response to DNA damage. |journal=Nat. Cell Biol. |volume=6 |issue= 10 |pages= 1003–9 |year= 2004 |pmid= 15448697 |doi= 10.1038/ncb1172
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Nag A, Bagchi S, Raychaudhuri P |title=Cul4A physically associates with MDM2 and participates in the proteolysis of p53. |journal=Cancer Res. |volume=64 |issue= 22 |pages= 8152–5 |year= 2005 |pmid= 15548678 |doi= 10.1158/0008-5472.CAN-04-2598
*cite journal | author=Matsuda N, Azuma K, Saijo M, "et al." |title=DDB2, the xeroderma pigmentosum group E gene product, is directly ubiquitylated by Cullin 4A-based ubiquitin ligase complex. |journal=DNA Repair (Amst.) |volume=4 |issue= 5 |pages= 537–45 |year= 2005 |pmid= 15811626 |doi= 10.1016/j.dnarep.2004.12.012

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes