L-aspartate oxidase

In enzymology, a L-aspartate oxidase (EC number|1.4.3.16) is an enzyme that catalyzes the chemical reaction

:L-aspartate + H₂O + O₂ $ightleftharpoons$ oxaloacetate + NH₃ + H₂O₂

The 3 substrates of this enzyme are L-aspartate, H₂O, and O₂, whereas its 3 products are oxaloacetate, NH₃, and H₂O₂.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with oxygen as acceptor. The systematic name of this enzyme class is L-aspartate:oxygen oxidoreductase (deaminating). This enzyme participates in alanine and aspartate metabolism and nicotinate and nicotinamide metabolism. It employs one cofactor, FAD.

tructural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1J5P, PDB link|1KNP, and PDB link|1KNR.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|69106-47-4."

Gene Ontology (GO) codes